RecruitingNCT07096258

EMPATHY NSCLC: European Registry for Plasma-Based Molecular Profiling in Advanced NSCLC Patients

A Patient Registry Collecting the Clinical and Molecular Profiling Data of Patients With Locally Advanced and/or Metastatic, Unresectable, Stages IIIB/C or IV Non-small Cell Lung Cancer (NSCLC), Who Have Not Previously Been Treated for This Advanced Disease and Are Therefore Considered as Patients Receiving First-line Therapy.


Sponsor

Hedera Dx SA

Enrollment

1,000 participants

Start Date

Jun 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this registry is to capture real-world data from plasma- and tissue-based molecular profiling, treatments, outcomes and patient-reported outcomes from patients with advanced or metastatic non-small cell lung cancer (NSCLC). The main objective of the study is to better understand the real-world clinical practice of the use and utility of molecular tumour profiling, the choice of treatment, and the outcome after such molecular profiling and treatment.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Locally advanced or metastatic, unresectable NSCLC, stages IIIB/C or IV, who have not previously been treated for this advanced disease.
  • Intention-to-initiate first-line tumour therapy for this advanced disease.
  • Eastern Cooperative Oncology Group (ECOG) performance status ≤ 2.
  • At least 18 years of age on the day of signing informed consent, and capable of signing informed consent.

Exclusion Criteria1

  • Any known non-cutaneous malignancy (except for this NSCLC and early-stage non-invasive cervical cancer) that has occurred within 5 years prior to enrolment.

Locations(4)

Université de Lorraine

Nancy, Lorraine, France

University of Naples "Federico II"

Napoli, Italy

General Universitario Gregorio Marañon

Madrid, Spain

Hôpitaux Universitaires Genève

Geneva, Canton of Geneva, Switzerland

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NCT07096258


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