Virus Transmission to People Recently Bitten or With a History of Monkey Bites "SIMVIR
Virus Transmission to People Recently Bitten or With a History of Monkey Bites "SIMVIR"
Institut Pasteur
80 participants
Aug 14, 2025
INTERVENTIONAL
Conditions
Summary
Nonhuman primates (NHPs) constitute an important reservoir of infectious agents, some of which have emerged in human populations as deadly pathogens. Human exposure to the biological fluids of NHPs - particularly through bites - can result in the transmission of several viruses. Only the rabies virus is currently targeted by post-exposure prophylaxis following an injury caused by an NHP. The objective of the study is to investigate the prevalence of STLV-1 and SFV infections following a nonhuman primate bite.
Eligibility
Inclusion Criteria6
- Age ≥ 18 years
- Bite inflicted by an HNP (WHO category 3 level)
- Written informed consent
- Affiliation with a social security scheme (excluding State Medical Aid
- Specific criteria for genetic analyses:
- Participant has checked the boxes for participation in the genetic component.
Exclusion Criteria5
- Patient presenting only with scratches inflicted by a PNH
- Medical management incompatible with the objectives of the study
- Patient who, in the doctor's opinion, is unlikely to comply with the study protocol
- Health conditions are incompatible with the sample collection required by the study
- Patient under legal protection (guardianship or trusteeship)
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Interventions
Blood samples of 40 ml will be taken.
Saliva samples will be collected
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07097480