RecruitingNot ApplicableNCT07099027

The Lung Health Check Pilot


Sponsor

Royal College of Surgeons, Ireland

Enrollment

2,183 participants

Start Date

May 19, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to test if it is feasible to introduce lung cancer screening in Ireland. People within a certain age group, who smoke or who smoked in the past, are at a greater risk of developing lung cancer. They can also develop chronic lung conditions that can affect their long-term health. In Ireland, about 2,690 people are diagnosed with Lung Cancer every year. Unfortunately, 2 out of every 3 people diagnosed with lung cancer die per year. The goal of this study is to try to screen for lung cancer in people before they have symptoms associated with the disease. We aim to do this by selecting people based on their age, whether they have smoked in the past or currently smoke as well as other relevant factors. People who take part in this study will have an assessment of how their lungs work and a low-dose CT scan. This is called a lung health check. The goal of the low-dose CT scan is to pick up lung cancer before it becomes symptomatic, and at an earlier stage. This scan uses a very low dose of radiation. Unfortunately, without early detection, such as is the goal of this trial, 8 out of 10 people who go on to develop lung cancer will have advanced lung cancer when it is discovered, where outcomes tend to be poor. The earlier detection of lung cancer has a greater potential for treatment. Current international recommendations suggest carrying out these scans in the community rather than in a hospital. Therefore, we aim to deliver these lung health checks using a mobile unit in the community. This study aims to test if we will successfully pick up lung cancer earlier by doing community-based 'lung health check's using mobile units in North Dublin and the North East, among people of a certain age and smoking history.


Eligibility

Min Age: 55 YearsMax Age: 74 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying a lung health check program that uses low-dose CT scans to screen for lung cancer in people who smoke or used to smoke. You may be eligible if... - You are between 55 and 74 years old - You are a current or former smoker (more than 100 cigarettes in your lifetime) - Your doctor has referred you to the Lung Health Check pilot - Your lung cancer risk score meets the required threshold You may NOT be eligible if... - You have had a chest CT scan in the past 12 months - You cannot lie flat or weigh more than 200 kg (which makes CT scanning difficult) - You have been diagnosed with advanced cancer or lung cancer in the past 5 years - You are unable or unwilling to attend study visits or give consent - You live in a nursing home Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTLow dose CT

In this arm, participants will undergo a respiratory assessment, smoking cessation, low-dose CT and biospecimen for translational research.


Locations(1)

Beaumont RCSI Cancer Centre

Dublin, Ireland

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NCT07099027


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