RecruitingPhase 4NCT07102615

Intracervical Vasopressin

Intracervical Vasopressin for Completion of Hysteroscopic Removal of Retained Products of Conception


Sponsor

Prisma Health-Upstate

Enrollment

50 participants

Start Date

Oct 30, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This randomized study looks at whether using a medicine injected into the cervix of the uterus (intracervical), called vasopressin, helps to achieve better removal of retained products of conception (RPOC). RPOC means that after a pregnancy has ended (through miscarriage, abortion, or delivery), some parts of the pregnancy tissue, usually from the placenta or fetus, have stayed in the uterus. A hysteroscopic removal of RPOC is one type of treatment. This is a surgical procedure where a doctor uses a small camera attached to a thin tube (called a hysteroscope) to look inside the uterus. The main goal of the study is : • To add to the existing research through this study to see if the injection of intracervical vasopressin leads to improved completion rates of hysteroscopic management of RPOC. Participants will: • would be randomized to receive either vasopressin intracervical injection or a placebo injection (non-active saline) during your procedure. Information from the procedure will be collected from the participant's medical record.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 51 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Intracervical Injection of saline and a drug called Intracervical injection of Vasopressin for people with retained products of conception. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGIntracervical injection of Vasopressin

Intracervical injection of Vasopressin

DRUGIntracervical Injection of saline

Intracervical Injection of saline


Locations(1)

The OB/GYN Center

Greenville, South Carolina, United States

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NCT07102615


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