A Study Evaluating Neoadjuvant Chemotherapy, Concurrent Chemoradiotherapy Combined With Dual Immune Checkpoint Blockade in Patients With Locally Advanced Non-Small Cell Lung Cancer

This study is testing whether combining chemotherapy before and during radiation therapy with two immunotherapy drugs can improve outcomes for people with Stage III non-small cell lung cancer that cannot be surgically removed. **You may be eligible if...** - You are between 18 and 75 years old - You have been diagnosed with Stage III non-small cell lung cancer that cannot be removed by surgery - Your cancer does not have EGFR, ALK, or ROS1 mutations - You have not received any prior treatment for this lung cancer - Your breathing and organ function are within acceptable levels **You may NOT be eligible if...** - You have already received chemotherapy, radiation, surgery, or immunotherapy for this cancer - You have certain lung function limitations - You are breastfeeding or unwilling to use contraception - Your organ function is too compromised Talk to your doctor to see if this trial is right for you.