Substance Use in Pregnant People - Optimizing Retention in Treatment
Substance Use in Pregnant People - Optimizing Retention in Treatment by Maximizing Opportunities for Management
Washington University School of Medicine
40 participants
Feb 2, 2026
INTERVENTIONAL
Conditions
Summary
Substance use during pregnancy is a leading cause of maternal morbidity and mortality in the United States, with 55-80% of postpartum patients disengaging from substance use disorder (SUD) treatment within one year of delivery. Structural and social determinants of health, including housing instability, transportation barriers, and limited childcare access, further exacerbate disparities in treatment retention. This pilot study, conducted in two specialized prenatal care clinics, evaluates the feasibility and acceptability of two integrated strategies to promote sustained engagement in recovery-oriented services during the perinatal and postpartum periods. Aim 1 implements a standardized social needs screening and referral protocol to connect patients with community-based supports. Aim 2 pilots a contingency management intervention to incentivize recovery-supportive behaviors. Findings will inform the design of a larger multi-site randomized controlled trial to evaluate the impact of these interventions on treatment retention, overdose prevention, and maternal-infant health outcomes.
Eligibility
Inclusion Criteria2
- Confirmed viable intrauterine pregnancy at any gestational age, or within three years postpartum
- SUD as defined in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders or clinician documentation
Exclusion Criteria2
- Decline follow-up care at study site
- Require immediate hospitalization for unstable medical or psychiatric conditions making them clinically unsuitable to participate in a research study
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Interventions
Patients will undergo a structured and protocoled screening for social drivers of health and be linked to support services
Patients will enter into a 12 week program of contingency management
Locations(2)
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NCT07104123