RecruitingEarly Phase 1NCT07106814
Safety and Efficacy of Metabolically Armed Tumor-lnfiltrating Lymphocytes (Meta10-TIL) for the Treatment of Advanced Solid Tumors
Sponsor
Anhui Provincial Hospital
Enrollment
36 participants
Start Date
Aug 29, 2025
Study Type
INTERVENTIONAL
Conditions
Summary
A Study of Metabolically Armed Tumor-Infiltrating Lymphocytes (Meta10-TIL) Therapy for Patients With Advanced Solid Tumors
Eligibility
Min Age: 19 YearsMax Age: 70 Years
Plain Language Summary
Simplified for easier understanding
This study is testing a new type of immune cell therapy called Meta10-TIL (tumor-infiltrating lymphocytes that have been metabolically enhanced) for people with advanced solid tumors, particularly cervical cancer and other hard-to-treat cancers. These are the patient's own immune cells that are removed, enhanced in a lab, and then put back into the body to fight cancer.
**You may be eligible if:**
- You are between 18 and 70 years old
- You have a confirmed advanced solid tumor (especially recurrent or metastatic cervical cancer)
- You have already received at least one prior line of treatment
- You have not had more than 3 prior systemic therapies
- Your cancer cannot be cured by surgery or radiation
**You may NOT be eligible if:**
- You have not yet received any prior treatment
- You have had more than 3 prior systemic therapies
- You have serious organ problems that would make this treatment unsafe
- You have active autoimmune disease or serious infections
Talk to your doctor to see if this trial is right for you.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
DRUGMetabolically Armed TIL cells
Each subject receive metabolically armed TIL cells by intravenous infusion.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07106814
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