Prosthetic Joint Infection : Lessons From Deceased Patients in Critical Care.
Osteoarticular Sepsis In Intensive Care Units : a Retrospective Study About Deceased Patients.
Assistance Publique - Hôpitaux de Paris
150 participants
Sep 24, 2025
OBSERVATIONAL
Conditions
Summary
This is an observational, retrospective, multicenter study based on the use of demographic, clinical and biological data from deceased patients admitted between 2018 and 2022 to critical care with a principal or associated diagnosis of joint prosthesis infection. Data from this study will be combined with that from the OASIS study (APHP241174/ ID-RCB: 2024-A01769-38) concerning osteoarticular sepsis on prosthetic material in critical care of living patients. The aim of this study is to improve our knowledge of the profile, care trajectories and outcomes of patients hospitalized in critical care in the context of osteoarticular material sepsis. The results of the study could help identify at-risk populations and improve management strategies for patients with osteoarticular sepsis.
Eligibility
Inclusion Criteria3
- Patient aged 18 years or older.
- Hospitalization in critical care (intensive care unit or continuing care unit) between 2018 and 2022, lasting at least 48 hours, with a prosthetic joint infection (hip, knee, or shoulder prosthesis infection) as the primary or associated diagnosis.
- Deceased patient who had not refused data processing.
Exclusion Criteria7
- Infection involving osteosynthesis material
- Infection involving spinal instrumentation
- Patient with multiple infected prostheses
- Recurrence of prosthetic infection with the same microorganism as a previous episode
- Patient under legal protection
- Pregnant or breastfeeding patient
- Patient deprived of liberty
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Interventions
All deceased patients admitted to intensive care during the study period and satisfying the eligibility criteria.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07107685