RecruitingNot ApplicableNCT07108400

Efficacy of a Combination of Ultrasound-guided Intra-articular Injections of Hyaluronic Acid, High-power Laser Therapy and Rehabilitation on Functioning in Patients Affected by Hip Osteoarthritis.

Efficacy of a Combination of Ultrasound-guided Intra-articular Injections of Hyaluronic Acid, High-power Laser Therapy and Rehabilitation on Functioning in Patients Affected by Hip Osteoarthritis: a Randomized Controlled Trial


Sponsor

De Sire Alessandro

Enrollment

57 participants

Start Date

Mar 17, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

High-power laser therapy (HPLT) is effective in treating musculoskeletal conditions, reducing pain and improving joint functionality. This randomized controlled trial (RCT) aimed to explore the effectiveness of a combination of HPLT, hyaluronic acid injections, and rehabilitation for patients with hip osteoarthritis.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria5

  • Age over 18 years
  • Diagnosis of hip OA (stage ≤ 3 according to the Kellgren and Lawrence classification)
  • Hip pain assessed with the Numeric Rating Scale ≥ 4
  • Body mass index (BMI) less than 30 kg/m²
  • Suspension of anti-inflammatory drugs (NSAIDs), opioids, corticosteroids, muscle relaxants or any other therapy that could interfere with the study assessments.

Exclusion Criteria2

  • Mini-Mental State Examination (MMSE) score < 24
  • Concurrent treatment with an-ti-inflammatory drugs or rehabilitation therapies; Rheumatoid arthritis.

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Interventions

PROCEDUREultrasound-guided injections of hyaluronic acid plus high-power laser therapy

Received two ultrasound-guided injections of hyaluronic acid into the coxo-femoral joint, 10 sessions of physical therapy specifically targeting hip OA (5 sessions/week for two weeks) lasting 45 minutes, and 10 sessions of active high-power laser therapy using a diode laser.

PROCEDUREultrasound-guided injections of hyaluronic acid plus sham" high-power laser therapy

Received two ultrasound-guided injections of hyaluronic acid into the coxo-femoral joint, 10 sessions of physical therapy specifically targeting hip OA (5 sessions/week for two weeks) lasting 45 minutes, and 10 sessions of "sham" high-power laser therapy using a diode laser, due to the presence of a light pointer and an acoustic signal of the device, which made it impossible to distinguish the active treatment from the sim-ulated one.


Locations(2)

University "Magna Graecia "of Catanzaro

Catanzaro, CZ, Italy

University "Magna Graecia "of Catanzaro

Catanzaro, Italy

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NCT07108400


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