RecruitingNCT07108725

Non-invasive Diffusion-weighted Imaging With MRCP in the Diagnosis of Neoplastic Biliary Obstruction

The Role of Non-invasive Diffusion-weighted Imaging With MRCP in the Diagnosis of Neoplastic Biliary Obstruction

Sponsor

The General Authority for Teaching Hospitals and Institutes

Enrollment

100 participants

Start Date

May 1, 2025

Study Type

OBSERVATIONAL

Conditions

Diagnosis Non-invasive Diffusion-weighted Imaging Magnetic Resonance Cholangiopancreatography Neoplastic Biliary Obstruction

Summary

This study aims to evaluate the diagnostic value of non-invasive diffusion-weighted magnetic resonance imaging (DW-MRI) in detecting neoplastic biliary obstruction.

Eligibility

Min Age: 18 Years

Inclusion Criteria3

Adult patients (≥18 years) with clinically suspected biliary obstruction (e.g., jaundice, elevated liver enzymes, cholestasis).
Patients who are scheduled for magnetic resonance cholangiopancreatography (MRCP) and have undergone conventional imaging \[ultrasound or computed tomography (CT)\].
Patients who will undergo further invasive procedures, e.g., endoscopic retrograde cholangiopancreatography (ERCP), biopsy.

Exclusion Criteria3

Patients with contraindications to magnetic resonance imaging (MRI) (e.g., pacemakers, metal implants).
Patients who have previously undergone major biliary surgery or stent placement.
Pregnant or lactating women.

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