RecruitingNot ApplicableNCT07109427

Impact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health System


Sponsor

Washington University School of Medicine

Enrollment

40,000 participants

Start Date

Aug 11, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

\- The investigators propose a clinical trial to evaluate the impact of annual shared decision making for PSA screening, supported by system-level enhancements to promote evidence-based care: * Defined referral thresholds within the health maintenance reminder, aligned with clinical risk stratification per NCCN guidelines. * Enhanced clinical decision support (CDS) tools to reduce provider variation and ensure guideline-concordant screening and referral practices. * The goal is to reduce late-stage presentation without increasing overdiagnosis-ensuring that prostate cancer screening is both accessible and clinically effective.


Eligibility

Sex: MALEMin Age: 40 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying whether adding a reminder alert in electronic health records encourages doctors to offer prostate-specific antigen (PSA) blood tests to men at appropriate risk for prostate cancer. You may be eligible if: you are a male patient who receives care at the BJC Health System; you have had at least one primary care visit in the relevant calendar year; you do not have a history of prostate cancer; and you are either an African American man between 40 and 75, have a family history of certain cancers, carry a known hereditary mutation, or are any man between 50 and 75 at average risk. You may NOT be eligible if: you have a prior history of prostate cancer. Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERAnnual PSA Health Maintenance Reminder

The annual health maintenance reminder does not mandate PSA screening for eligible patients. Instead, it recommends that primary care providers (PCPs) initiate a shared decision-making discussion with their patients. As part of this conversation, patients will be informed of their individual risk factors-including race, family history, and germline mutations-and can then make an informed choice about whether to proceed with PSA screening.


Locations(1)

Washington University School of Medicine

St Louis, Missouri, United States

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NCT07109427


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