RecruitingNCT07112989

Development of Innovative Preclinical Ex Vivo Models for the Study of Sarcomas and Metastases From Solid Tumors


Sponsor

Istituto Ortopedico Rizzoli

Enrollment

125 participants

Start Date

Sep 23, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to learn how tumor tissue and blood samples from patients with sarcomas or metastases can be used to create laboratory models that help researchers study cancer behavior and test new treatments. Participants diagnosed with sarcoma or with bone or lung metastases from solid tumors will donate leftover tumor tissue and blood collected during their regular medical care. These samples will be used in the lab to build 3D models of the tumor, test drugs, and identify genetic and molecular markers. No treatments or procedures will be given as part of the study.


Eligibility

Max Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study is creating laboratory models from actual patient tumor tissue (sarcomas and bone/lung metastases from solid tumors) to better study how these cancers behave and respond to treatments outside the body. These 'ex vivo' models can help researchers develop better therapies without testing on patients directly. **You may be eligible if...** - You are between 0 and 85 years old - You have been diagnosed with a sarcoma (a type of connective tissue cancer) or have bone or lung metastases from another solid tumor cancer - Sufficient tumor tissue or blood samples can be collected during your planned procedure - You have signed the required informed consent for tissue/blood use in research and biobanking **You may NOT be eligible if...** - Your diagnosis is not a sarcoma or metastases from a solid tumor - You have not signed the required consent forms Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Istituto Ortopedico Rizzoli

Bologna, Italy

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NCT07112989


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