Investigation of Cold Snare Polypectomy for Removing 10-20 mm 0-Ip Colorectal Polyp
Investigation of Cold Snare Polypectomy for Removing 10-20 mm 0-Ip Colorectal Polyp: One Feasibility and Safety Study
National Taiwan University Hospital
120 participants
Aug 25, 2025
INTERVENTIONAL
Conditions
Summary
This is a multicenter, single-arm feasibility study conducted across multiple hospitals in Taiwan. The goal of this trial is to evaluate whether cold snare polypectomy is a feasible and safe method for removing 10-20 mm pedunculated colorectal polyps. The main questions it aims to answer are: 1. Can cold snare polypectomy achieve complete removal of 10-20 mm pedunculated polyps? 2. What are the rates and types of complications associated with this technique? Participants will: 1. Undergo colonoscopy as clinically indicated 2. Have 10-20 mm pedunculated polyps removed using cold snare polypectomy if eligible 3. Be monitored for post-procedure outcomes, including pathology results and any complications
Eligibility
Inclusion Criteria3
- Age ≥ 20 years
- Undergoing colonoscopy for any clinical indication
- Found to have a 10-20 mm pedunculated colorectal polyp suitable for cold snare polypectomy
Exclusion Criteria3
- Age < 20 years
- Medical contraindications to colonoscopy or polypectomy (e.g., recent myocardial infarction, stroke, severe unstable cardiovascular disease, acute peritonitis, fulminant colitis, perforation, or toxic megacolon)
- Inadequate bowel preparation preventing complete colonoscopy or safe polypectomy
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Interventions
Unlike traditional hot snare polypectomy or endoscopic mucosal resection, which use electrocautery to resect larger or pedunculated polyps, cold snare polypectomy uses mechanical transection alone without cautery. The procedure is performed using a dedicated cold snare by experienced endoscopists.
Locations(5)
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NCT07114380