RecruitingNot ApplicableNCT07114380

Investigation of Cold Snare Polypectomy for Removing 10-20 mm 0-Ip Colorectal Polyp

Investigation of Cold Snare Polypectomy for Removing 10-20 mm 0-Ip Colorectal Polyp: One Feasibility and Safety Study


Sponsor

National Taiwan University Hospital

Enrollment

120 participants

Start Date

Aug 25, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This is a multicenter, single-arm feasibility study conducted across multiple hospitals in Taiwan. The goal of this trial is to evaluate whether cold snare polypectomy is a feasible and safe method for removing 10-20 mm pedunculated colorectal polyps. The main questions it aims to answer are: 1. Can cold snare polypectomy achieve complete removal of 10-20 mm pedunculated polyps? 2. What are the rates and types of complications associated with this technique? Participants will: 1. Undergo colonoscopy as clinically indicated 2. Have 10-20 mm pedunculated polyps removed using cold snare polypectomy if eligible 3. Be monitored for post-procedure outcomes, including pathology results and any complications


Eligibility

Min Age: 20 Years

Inclusion Criteria3

  • Age ≥ 20 years
  • Undergoing colonoscopy for any clinical indication
  • Found to have a 10-20 mm pedunculated colorectal polyp suitable for cold snare polypectomy

Exclusion Criteria3

  • Age < 20 years
  • Medical contraindications to colonoscopy or polypectomy (e.g., recent myocardial infarction, stroke, severe unstable cardiovascular disease, acute peritonitis, fulminant colitis, perforation, or toxic megacolon)
  • Inadequate bowel preparation preventing complete colonoscopy or safe polypectomy

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Interventions

DEVICECold snare polypectomy

Unlike traditional hot snare polypectomy or endoscopic mucosal resection, which use electrocautery to resect larger or pedunculated polyps, cold snare polypectomy uses mechanical transection alone without cautery. The procedure is performed using a dedicated cold snare by experienced endoscopists.


Locations(5)

National Taiwan University Hospital Hsin-Chu Branch

Hsinchu, Taiwan

National Taiwan University Hospital, Jinshan Branch

New Taipei City, Taiwan

National Taiwan University Cancer Center

Taipei, Taiwan

National Taiwan University Hospital, Bei-Hu Branch

Taipei, Taiwan

National Taiwan University Hospital

Taipei, Taiwan

View Full Details on ClinicalTrials.gov

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NCT07114380