RecruitingNCT07114653

The Role of POLE Mutation in High Risk Endometrial Cancer.

Sponsor

Far Eastern Memorial Hospital

Enrollment

150 participants

Start Date

Sep 1, 2025

Study Type

OBSERVATIONAL

Conditions

Endometrial Neoplasms

Summary

The actual role of POLE mutations in high-risk endometrial cancer is undetermined. The main question it aims to answer is: What is the prevalence of POLE mutations in high-risk endometrial cancer case? What is the impact of POLE mutations in real world high-risk endometrial cancer case?

Eligibility

Sex: FEMALE

Plain Language Summary

Simplified for easier understanding

This is an observational study looking at how a specific genetic mutation called POLE affects outcomes in women with high-risk endometrial cancer (cancer of the uterine lining). Researchers want to better understand who is at greatest risk of recurrence. **You may be eligible if...** - You are a woman with endometrial cancer that is considered high-risk for recurrence - Your doctor has referred you for inclusion in this research study **You may NOT be eligible if...** - There are no specific exclusion criteria listed for this study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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