RecruitingPhase 3NCT07115004

Study to Evaluate Subcutaneous (SC) VGA039 in Patients With Von Willebrand Disease (VWD)

A Prospective, Multicenter, Open-label, Phase 3 Clinical Study to Evaluate the Efficacy and Safety of Prophylactic VGA039 in Adolescent and Adult Patients With Von Willebrand Disease (VIVID-6)

Sponsor

Vega Therapeutics, Inc

Enrollment

60 participants

Start Date

Oct 15, 2025

Study Type

INTERVENTIONAL

Conditions

Von Willebrand Disease (vWD)

Summary

This is a phase 3 study that will evaluate subcutaneous (SC) VGA039 in patients with von Willebrand Disease (VWD)

Eligibility

Min Age: 12 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called VGA039 for people with von willebrand disease (vwd). The study is currently recruiting participants at 14 locations. People eligible for this study include aged 12 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGVGA039

VGA039 SC administered for 49-weeks during the interventional phase following a 24-week observational period.

Locations(14)

Arkansas Children's Hospital

Little Rock, Arkansas, United States

Luskin Orthopaedic Institute For Children

Los Angeles, California, United States

UC Davis Medical Center

Sacramento, California, United States

University of California San Francisco

San Francisco, California, United States

Emory University Hospital

Atlanta, Georgia, United States

Children's Healthcare of Atlanta

Atlanta, Georgia, United States

University of Minnesota

Minneapolis, Minnesota, United States

Science 37, Inc. (Virtual Clinical MetaSite)

Morrisville, North Carolina, United States

Hemophilia Center of Western PA

Pittsburgh, Pennsylvania, United States

UT Southwestern Children's Hospital

Dallas, Texas, United States

Washington Center for Bleeding Disorders

Seattle, Washington, United States

K Eristavi National Center of Experimental and Clinical Surgery (ქირურგიის ეროვნული ცენტრი)

Tbilisi, Georgia

Frankfurt University Hospital (Universitätsmedizin Frankfurt)

Frankfurt, Germany

Charlotte Maxeke Johannesburg Academic Hospital School of Pathology Clinical Haematologist

Johannesburg, South Africa

View Full Details on ClinicalTrials.gov

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NCT07115004

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