Effects of Pomegranate Juice on Ulcerative Colitis

This trial investigates whether drinking pomegranate juice daily can reduce inflammation and improve symptoms in adults with mild-to-moderate ulcerative colitis (UC), an inflammatory bowel disease. Pomegranate is rich in compounds called polyphenols that may have anti-inflammatory effects. **You may be eligible if...** - You are 18 or older - You have confirmed ulcerative colitis with mild-to-moderate active disease (partial Mayo score 2–5) - You currently eat few fruits and vegetables (less than 3 servings per day) - You have blood or stool markers showing active inflammation - Any medications for UC (such as mesalazine or immunosuppressants) have been at a stable dose for several weeks **You may NOT be eligible if...** - You do not speak English - You are vegetarian or vegan - You have a pomegranate allergy - You have other serious chronic diseases (diabetes, kidney disease, active cancer, history of heart attack or stroke) - You have severe or fulminant colitis, Crohn's disease, or have had bowel surgery - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.