RecruitingPhase 1NCT07116486

A Trial Utilizing 18F-FS PG PET to Guide Therapy in Hepatocellular Carcinoma

Phase 1, Single-site, Single-arm, Clinical Imaging, and Blood-based Biomarker Trial Utilizing 18F-FSPG PET to Guide Therapy in Hepatocellular Carcinoma


Sponsor

M.D. Anderson Cancer Center

Enrollment

60 participants

Start Date

Dec 2, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

To evaluate the relationship between 18F-FSPG uptake in HCC lesions, ctDNA in blood and clinical response to Y90 radioembolization therapy in patients with hepatocellular carcinoma (HCC) by SOC imaging.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial uses a new experimental PET scan tracer called 18F-FSPG to see how well it can detect liver cancer (hepatocellular carcinoma, or HCC) and guide a targeted radiation treatment called Y90 radioembolization, where tiny radioactive beads are injected into the blood vessels feeding the tumor. **You may be eligible if...** - You are 18 or older - You have a confirmed or highly suspected diagnosis of hepatocellular carcinoma (liver cancer) - You are a candidate for Y90 radioembolization treatment - You have already completed standard imaging and staging **You may NOT be eligible if...** - Your liver cancer was previously treated and has not yet progressed again - You are pregnant or planning to become pregnant - You are unable to lie still during the scan - You have other serious medical conditions that make participation unsafe Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DIAGNOSTIC_TESTRadiopharmaceutical 18F-FSPG

Given by injection


Locations(1)

The University of Texas M. D. Anderson Cancer Center

Houston, Texas, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07116486


Related Trials