RecruitingPhase 4NCT07119398

Oxytocin/Foley vs. Oxytocin for Induction in Patients With PPROM

Combination Oxytocin/Foley Versus Oxytocin Alone for Induction of Labor in Patients With Preterm Prelabor Rupture of Membranes


Sponsor

Eastern Virginia Medical School

Enrollment

80 participants

Start Date

Jul 14, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Data on the optimal mode of labor induction after preterm prelabor rupture of membranes (PPROM) is lacking. Studies have shown no difference between oxytocin and misoprostol use for labor induction in this cohort (1). The preponderance of evidence from term pregnancies suggests that Foley catheter coupled with oxytocin is better than oxytocin alone, with a higher rate of delivery within 24 hours when a Foley catheter followed by oxytocin is compared to oxytocin alone. However, the use of a Foley catheter has not been evaluated in prospective studies on patients with PPROM.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Oxytocin and Oxytocin plus Foley Catheter for people with preterm prom (pregnancy). The study is currently recruiting participants at 1 location. People eligible for this study include women aged 18 Years to 50 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

COMBINATION_PRODUCTOxytocin plus Foley Catheter

Intravenous oxytocin and a transcervical Foley catheter

DRUGOxytocin

Intravenous oxytocin


Locations(1)

Sentara Norfolk General Hospital

Norfolk, Virginia, United States

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NCT07119398


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