RecruitingNCT07121543

Biological Drivers of Cervical Cancer and Side Effects From Radiation Therapy

Understanding the Biological Drivers of Cervical Cancer and Side Effects From Radiation Therapy

Sponsor

University of California, San Diego

Enrollment

20 participants

Start Date

Aug 4, 2025

Study Type

OBSERVATIONAL

Conditions

Cervical Cancer

Summary

The goal of this observational study is to learn more about the biology of cervical cancer in women who receive radiation therapy for this condition. The main question it aims to answer is: Does radiation therapy alter the expression of tissue factor and other molecules in cervical cancer over time? Participants already scheduled for radiation therapy for cervical cancer as part of their regular medical care will provide blood and biopsies of cervical cancer or of the upper portion of the vagina before, during, and on the last day of radiation therapy.

Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating the biological factors that drive cervical cancer and the side effects caused by brachytherapy (internal radiation treatment). Researchers will collect tissue and blood samples to better understand what biological markers predict cancer behavior and which patients are more likely to experience treatment-related side effects. **You may be eligible if...** - You are 18 or older with a confirmed pathological diagnosis of cervical cancer - You are scheduled to receive brachytherapy as part of your cancer treatment - You are willing to provide a tissue sample for research **You may NOT be eligible if...** - You are pregnant or breastfeeding - You are unable to provide a tissue sample Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONBrachytherapy

Brachytherapy is a cancer treatment where radioactive sources are placed inside or near the tumor.

Locations(1)

University of California San Diego

La Jolla, California, United States

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NCT07121543

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