RecruitingNCT07121543

Biological Drivers of Cervical Cancer and Side Effects From Radiation Therapy

Understanding the Biological Drivers of Cervical Cancer and Side Effects From Radiation Therapy


Sponsor

University of California, San Diego

Enrollment

20 participants

Start Date

Aug 4, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to learn more about the biology of cervical cancer in women who receive radiation therapy for this condition. The main question it aims to answer is: Does radiation therapy alter the expression of tissue factor and other molecules in cervical cancer over time? Participants already scheduled for radiation therapy for cervical cancer as part of their regular medical care will provide blood and biopsies of cervical cancer or of the upper portion of the vagina before, during, and on the last day of radiation therapy.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria3

  • Age 18 years or older
  • Pathological diagnosis of cervical cancer
  • Scheduled to receive brachytherapy for cervical cancer

Exclusion Criteria2

  • Pregnancy or lactation
  • Inability to provide a tissue sample

Interventions

RADIATIONBrachytherapy

Brachytherapy is a cancer treatment where radioactive sources are placed inside or near the tumor.


Locations(1)

University of California San Diego

La Jolla, California, United States

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NCT07121543


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