RecruitingPhase 4NCT07123870

Effect of Combined Intravenous-Inhalational Anesthesia (CIVIA) on Postoperative Recovery Patterns.


Sponsor

Kocaeli City Hospital

Enrollment

210 participants

Start Date

Jul 23, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study was planned as a single-center, prospective, randomized trial. Adult patients undergoing elective spinal surgery lasting longer than three hours, performed in a neurosurgery operating room, will be evaluated. Patients managed with three different anesthesia methods currently used will be examined for recovery patterns: 1. Total intravenous anesthesia (TIVA), 2. TIVA Combined anesthesia with sevoflurane and intravenous agents (sevoflurane-CIVIA), 3. TIVA Combined anesthesia with desflurane and intravenous agents (desflurane-CIVIA). Recovery patterns include; extubation time, eye opening time, emergence agitation, postoperative nausia and vomiting and postoperative recovery unit discharge time.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Desflurane, a drug called Sevofluorane, and others for people with inhalation anesthesia, postoperative recovery, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSevofluorane

In this group of patients, \<0.5 MAC sevoflurane will be used in combination with TIVA. (TIVA method described above)

DRUGDesflurane

In this group of patients, \<0.5 MAC Desflurane will be used in combination with TIVA.

DRUGTotal Intravenous Anesthesia(TIVA)

In this group, TIVA will be applied with the combination of BIS-guided propofol + remifentanil.


Locations(1)

Kocaeli City Hospital

Kocaeli, Izmıt, Turkey (Türkiye)

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NCT07123870


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