RecruitingNCT07124572

Construction and Application of Precise Diagnosis and Treatment System for Thyroid-associated Ophthalmopathy

Sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Enrollment

500 participants

Start Date

Oct 1, 2022

Study Type

OBSERVATIONAL

Conditions

Thyroid Associated Ophthalmopathy

Summary

This study aims to develop the deep learning-based system that integrates multimodal information to automatically diagnose, stage, and grade thyroid-associated ophthalmopathy (TAO), assist in treatment decision-making, and predict patient prognosis, thereby providing novel tools to support clinical management.

Eligibility

Min Age: 7 YearsMax Age: 90 Years

Inclusion Criteria3

normal participants without eyelid disorders (control group)
patients with thyroid-associated ophthalmopathy (TAO group)
cooperative participants

Exclusion Criteria2

participants with pupil or cornea disorders
participants with history of eye injury

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Interventions

OTHERImaging and ocular examinations

2D and 3D Facial photography, blinking videos, orbital CT and MRI images, fundus images and images of nine gaze positions are taken. Clinical information is recorded. Quality of life is assessed. Ocular examinations, such as visual acuity, levator function, exophthalmos measurement, strabismus test, visual field examination, axial length measurement, OCT, OCTA are made.