RecruitingNot ApplicableNCT07126301

Aromatherapy Essential Oils to Manage Anxiety and Nausea in Cancer Patients Receiving Infusion in the Ambulatory Setting

Assessing the Feasibility of Aromatherapy Essential Oil Associated Changes on Nausea in Patients Receiving Infusion in the Ambulatory Setting


Sponsor

City of Hope Medical Center

Enrollment

60 participants

Start Date

Jul 8, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This clinical trial tests how well aromatherapy essential oils work to manage anxiety and nausea in cancer patients receiving infusions in the ambulatory setting. Current drugs that are given for nausea may cause constipation and fatigue. Therefore, there is interest in exploring complementary therapies, like aromatherapy, that do not carry the same side effects. Using aromatherapy essential oils such as ginger, peppermint, and lavender, may help reduce nausea and anxiety. Some studies have shown significant reductions in nausea and anxiety among cancer patients using these oils, while other studies have had mixed results. Ginger and peppermint oils, in particular, have been associated with helping reduce nausea during chemotherapy, while lavender has shown potential benefits for anxiety. Jojoba oil will be used as a placebo for this research study. Jojoba oil is extracted from the seeds of a jojoba plant, which is a green shrub that is found in the southwestern United States). Jojoba oil is an oil which has no color or smell. Aromatherapy essential oils used through a personal inhalation device during chemotherapy may better manage anxiety and nausea in cancer patients receiving infusions in the ambulatory setting.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether aromatherapy (using essential oils) can help reduce anxiety and nausea in cancer patients who are receiving treatment through an IV infusion in an outpatient setting. **You may be eligible if...** - You are 18 years or older - You have a cancer diagnosis and are receiving infusion therapy in an outpatient clinic - You are able to read and understand English - You are in reasonable overall health (ECOG performance status 0–2) - You are willing to try aromatherapy during your infusion visit **You may NOT be eligible if...** - You have a known allergy or sensitivity to essential oils or strong fragrances - You are not able to understand English for completing patient surveys - You are not receiving infusion therapy for cancer - You are pregnant or have other conditions that could be worsened by aromatherapy Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREAromatherapy and Essential Oils

Inhale peppermint oil

PROCEDUREAromatherapy and Essential Oils

Inhale lavender oil

PROCEDUREAromatherapy and Essential Oils

Inhale ginger oil

PROCEDUREAromatherapy and Essential Oils

Inhale placebo jojoba oil

OTHERQuestionnaire Administration

Ancillary studies


Locations(2)

City of Hope Medical Center

Duarte, California, United States

City of Hope at Irvine Lennar

Irvine, California, United States

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NCT07126301


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