RecruitingNot ApplicableNCT07126470

Impact of Capsular Tension Ring on Intraocular Lens Position in Retinitis Pigmentosa Cataract Patients

Effect of Capsular Tension Ring Implantation on Postoperative IOL Position in Retinitis Pigmentosa Patients With Cataract: a Multi-center, Randomized, Self-controlled Study

Sponsor

Zhongshan Ophthalmic Center, Sun Yat-sen University

Enrollment

88 participants

Start Date

Aug 25, 2025

Study Type

INTERVENTIONAL

Conditions

Cataract

Summary

This is a self-controlled randomized clinical trial to investigate the effect of capsular tension ring (CTR) implantation on intraocular lens (IOL) position in cataract patients with retinitis pigmentosa(RP). Each patient will receive CTR implantation in one eye, with the fellow eye serving as control. Postoperative outcomes, including visual acuity, IOL position, and postoperative complications will be compared between eyes.

Eligibility

Min Age: 18 Years

Inclusion Criteria4

Age ≥ 18 years.
Clinical diagnosis of retinitis pigmentosa (RP).
Bilateral cataract meeting the indications for IOL implantation.
Willingness to participate in the study and provision of signed informed consent.

Exclusion Criteria4

History of intraocular surgery.
Severe zonular weakness (e.g., zonular dialysis >90°, lens subluxation/dislocation)
Other ocular comorbidity: such as pseudoexfoliation syndrome, ocular trauma, corneal dystrophies, uveitis, etc.
Severe systemic diseases: such as severe hypertension, diabetes, heart disease, Alzheimer's, Parkinson, etc.

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Interventions

PROCEDURECTR implantation

Device: CTR (275001G, OPHTEC BV, Netherlands) All patients undergo uneventful phacoemulsification by a 2.2 mm temporal transparent corneal incision using Centurion Vision System (Alcon Laboratories, Fort Worth, TX, USA). After the nucleus and cortex are removed, a capsular tension ring is implanted in the capsular bag and then IOL (J\&J Tecnis DCB00) is implanted.