RecruitingNCT07126821

A Vision-Language Foundation Model for Brain Disease Diagnosis From Multimodal Data


Sponsor

Xiangya Hospital of Central South University

Enrollment

100,000 participants

Start Date

May 15, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to develop an innovative, comprehensive, and explainable AI vision-language foundation model (VLM) to advance the diagnosis and interpretation of brain diseases using multi-modal data. We will include patient demographics, medical imaging data (such as MRI, CT, and PET scans), histopathological data, genomic data when available, and other necessary laboratory examinations and tests to establish a screening and diagnostic model for brain diseases.


Eligibility

Inclusion Criteria6

  • Patients with brain diseases:
  • Patients with brain tumors were pathologically diagnosed.
  • Patients with other brain diseases were correctly diagnosed.
  • The clinical case data of all patients were complete.
  • Non-brain disease population:
  • All patients have complete clinical case data, complete brain MRI, no history brain diseases, no brain surgery or other brain diseases that affect the diagnosis and observation of MR imaging.

Exclusion Criteria1

  • Cases in which MRI were incomplete or with significant noise and artifacts.

Interventions

OTHERNo Interventions

No Interventions


Locations(1)

Xiangya Hospital of Central South University

Changsha, Hunan, China

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NCT07126821


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