RecruitingNot ApplicableNCT07134257

Smart Crutch Tips for Guided Weight-Bearing in Patients Recovering From Extra-Articular Proximal Tibia Fractures

Study of Individual Weight-bearing and Iterative Walking Using "ComeBack Mobility" Smart Crutch Tips for Mechanical Stimulation of Extra-articular Proximal Tibia Fracture Healing


Sponsor

Comeback Mobility Inc

Enrollment

30 participants

Start Date

Oct 20, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to learn whether personalized weight-bearing prescriptions using Smart Crutch Tips™ can improve recovery after surgery for extra-articular proximal tibia fractures. The study will also assess how safe and practical this approach is in daily outpatient use. Can a personalized weight-bearing program based on CT and finite element analysis help the fracture heal faster? Can it help patients return to full weight-bearing sooner? Can it reduce the fear of movement during recovery? Researchers will compare standard rehabilitation, AO Foundation-based recommendations, and personalized weight-bearing programs derived from finite element analysis (FEA) to determine which approach leads to faster healing, earlier mobility, and better outcomes. Participants will: Use Smart Crutch Tips™ during walking for up to 24 weeks; Follow a personalized weight-bearing prescription based on CT scans and biomechanical modeling; Follow a specific walking plan with real-time audio and visual feedback; Attend eight follow-up visits over 36 weeks for clinical exams, x-rays, and CT scans; Complete online questionnaires about pain, activity, and fear of movement.


Eligibility

Min Age: 18 YearsMax Age: 60 Years

Inclusion Criteria11

  • Signed informed consent was provided after being fully informed about participation in the study.
  • Age: 18 to 60 years for both males and females (pre-menopausal).
  • Body weight between 40 and 120 kg.
  • Diagnosed with a closed tibial shaft fracture (AO/OTA classification: 41-A2, 41-A3) requiring surgical treatment.
  • Fracture treated exclusively with a plate.
  • No diabetes or well-controlled diabetes (HbA1c ≤ 7.0%).
  • Ability to use crutches without losing balance and medically cleared for partial weight-bearing on the operated limb.
  • Willingness to adhere to the prescribed weight-bearing protocol using the Smart Crutch Tips™ device.
  • Enrollment within 48 hours following surgical intervention.
  • Alcohol consumption (up to 2-3 times per week) within acceptable limits.
  • Willingness to comply with all study procedures, including follow-up visits at weeks 1, 4, 8, 12, 15, 18, 24, and 36 after surgery.

Exclusion Criteria16

  • Presence of open or high-energy fractures, multiple lower-limb fractures, or use of bone grafts.
  • Fractures classified as 43-B or 43-C according to AO/OTA.
  • Chronic alcoholism (defined as \>14 standard drinks per week for men or \>7 for women).
  • Presence of metabolic disorders, including uncontrolled thyroid dysfunction, severe renal or hepatic pathology.
  • Pathological fractures associated with osteoporosis, osteomyelitis, tumors, metastases, or rickets.
  • Lower-limb contractures with functional impairment of grade II or higher.
  • Pregnancy or intention to conceive during the study period.
  • Psychiatric, cognitive, or neurological disorders that may interfere with adherence to the rehabilitation protocol or effective communication with the study team.
  • Clinically significant heart failure (including chronic or acute, with an ejection fraction \<40% or with symptoms such as edema, dyspnea at rest, or orthopnea).
  • Pulmonary insufficiency of any origin, accompanied by chronic hypoxemia (PaO₂ \< 60 mmHg) or hypercapnia (PaCO₂ \> 45 mmHg), requiring oxygen support or significantly limiting physical activity.
  • Clinically significant neurological disorders that may affect motor function, coordination, or physical activity (e.g., stroke with residual deficits, Parkinson's disease, multiple sclerosis, cerebral palsy).
  • Diagnosed epilepsy or other seizure disorders not fully controlled by medication.
  • Progressive neurodegenerative diseases (e.g., amyotrophic lateral sclerosis, Huntington's disease, dementia).
  • Any sensory, balance, or vestibular disorders that may impair safe use of the investigational device.
  • Participation in another clinical study within the past 6 months that could affect the results of the current study.
  • Ongoing or planned use of medications known to affect bone healing.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DEVICESmart Crutch Tips™

Smart Crutch Tips™ are sensor-equipped crutch attachments that measure real-time axial loading during ambulation. The devices connect via Bluetooth to a mobile application and deliver auditory and visual feedback to guide patients toward prescribed weight-bearing levels. The devices continuously record loading and step-count data for clinical monitoring and analysis.

PROCEDUREFinite Element Analysis (FEA)

Finite Element Analysis (FEA) is performed up to four times postoperatively to generate individualized weight-bearing prescriptions during rehabilitation. Simulations are based on CT scans and include segmentation and biomechanical modeling of the bone-fixator system. Assessments occur at: 7 days (baseline), 4 weeks, 8 weeks, and optionally at 12 weeks. Three regions are segmented: fixation system (screws and nail), bone fragments, and fracture gap. Materials: fixator (Titanium Grade 5), bone (mapped into cortical, trabecular, soft tissue, air), and fracture gap (early connective tissue). FEA calculates personalized safe loading based on: (1) Fixator safety (stress \< 290 MPa), (2) Interfragmentary motion (target: 0.5-2.0 mm), and (3) Strain in the fracture gap (octahedral: 0.001-0.05; hydrostatic: 0.001-0.02), supporting biological healing. Output informs weight-bearing prescriptions and step-count targets, delivered via Smart Crutch Tips™ with real-time fee

BEHAVIORALIterative walking

Participants will perform iterative walking sessions as part of their rehabilitation program. These sessions will be repeated throughout the day, with a minimum 2-hour rest interval between sessions. Step count will be progressively increased over time, according to the individualized rehabilitation plan. In the intervention arms, walking sessions will be guided by real-time auditory and visual feedback from Smart Crutch Tips™.

PROCEDURELower Limb Rehabilitation Exercise Program

The program includes isometric and dynamic exercises targeting the quadriceps, hamstrings, gluteal muscles, and ankle/foot mobility to maintain muscle tone, prevent joint stiffness, reduce swelling, and improve circulation. All exercises are performed within a pain-free range (not exceeding 4/10 on the VAS scale) with gradual progression according to the rehabilitation plan.


Locations(11)

Kyiv City Clinical Hospital No. 1

Kyiv, Kyiv Oblast, Ukraine

Municipal Clinical Hospital No. 6 of the Dnipro City Counci

Dnipro, Ukraine

Municipal Clinical Hospital No. 4 of the Dnipro City Counci

Dnipro, Ukraine

Kyiv City Clinical Hospital No. 17

Kyiv, Ukraine

Institute of Traumatology and orthopedics of the national academy of medical sciences of Ukraine

Kyiv, Ukraine

Kyiv City Clinical Hospital No. 12

Kyiv, Ukraine

Kyiv City Clinical Hospital No. 6

Kyiv, Ukraine

Kyiv City Clinical Hospital No. 7

Kyiv, Ukraine

Kyiv Regional Council "Kyiv Regional Clinical Hospital"

Kyiv, Ukraine

Kyiv City Clinical Hospital No. 9

Kyiv, Ukraine

Kyiv City Clinical Hospital No. 8

Kyiv, Ukraine

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07134257