RecruitingNCT07134270

Infection Risk Associated With Digestive MDRO Carriage in Hospitalized Patients

Association Between Digestive MDRO Carriage and Infection Risk in Hospitalized Patients: A Single-Center Prospective Analysis


Sponsor

Valeriu Gheorghita

Enrollment

400 participants

Start Date

Jan 1, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to evaluate the impact of digestive carriage of multidrug-resistant organisms (MDRO) on the risk of healthcare-associated infections in hospitalized adult patients. Patients will be screened at admission, weekly, and at discharge, with a 30-day post-discharge follow-up. The findings will support infection prevention and control strategies in Romanian hospitals.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • years
  • Admitted to participating wards
  • Signed informed consent

Exclusion Criteria1

  • withdrawal

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Interventions

PROCEDUREMDRO Rectal Screening

Repeated rectal swab collection for screening digestive colonization with multidrug-resistant organisms (MDRO), performed at admission (or within 14 days prior), on day 7, weekly during hospitalization, and at discharge.

OTHER30-Day Telephone Follow-Up

Structured phone interview conducted 30 days post-discharge, using a standardized questionnaire assessing new infections, rehospitalizations, antibiotic use, and self-rated health status.


Locations(1)

Emergency and Clinical Hospital Dr. Agrippa Ionescu

Bucharest, Bucharest, Romania

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NCT07134270