RecruitingPhase 2NCT07135037

Comparison Between Treatments of Oligohydramnios

Efficacy of L- Arginine Versus Sildenafil in Management of Idiopathic Oligohydramnios


Sponsor

Kafrelsheikh University

Enrollment

40 participants

Start Date

Sep 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Based on previous studies, Both sildenafil and L-arginine helped to improve idiopathic oligohydramnios. In this study, Level of improvment of oligohydramnios will be compared. As well as, NICU admission to neonates of pregnancies complicated by idiopathic oligohydramnios. The end goal is to help physicians use the best drug for their patients.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 35 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called L-Arginine, 1000 Mg Oral Tablet and a drug called Sildenafil 25 MG for people with oligohydramnios. The study is currently recruiting participants at 2 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSildenafil 25 MG

Sildenafil is a vasodilator drug which improve blood supply to placenta.Therefore, it should improve idiopathic oligohydramnios.

DRUGL-Arginine, 1000 Mg Oral Tablet

Aminoacid with vasodilator property which improve blood supply to placenta.Therefore, it should improve idiopathic oligohydramnios.


Locations(2)

Kafrelsheikh University Hospital

Kafr ash Shaykh, Kafrelsheikh, Egypt

Kafrelsheokh university hospital

Kafr ash Shaykh, Kafrelsheikh, Egypt

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NCT07135037


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