RecruitingPhase 2NCT07135037

Comparison Between Treatments of Oligohydramnios

Efficacy of L- Arginine Versus Sildenafil in Management of Idiopathic Oligohydramnios

Sponsor

Kafrelsheikh University

Enrollment

40 participants

Start Date

Sep 1, 2024

Study Type

INTERVENTIONAL

Conditions

Oligohydramnios

Summary

Based on previous studies, Both sildenafil and L-arginine helped to improve idiopathic oligohydramnios. In this study, Level of improvment of oligohydramnios will be compared. As well as, NICU admission to neonates of pregnancies complicated by idiopathic oligohydramnios. The end goal is to help physicians use the best drug for their patients.

Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 35 Years

Inclusion Criteria5

Pregnant women with gestational age between 26-37 weeks
Pregnant women whose age is \< 35 years
Woman with other indication for elective caesarean section.
Women carrying a single fetus with no major anomalies.
Initial amniotic fluid index \<8cm determined by reliable pelivabdominal ultrasound.

Exclusion Criteria5

Women complaining of other obstetric disorder such as, PPROM, preeclampsia, or diabetes.
Women with chronic illness such as, chronic hypertension, autoimmune disease or kidney disease.
Women who received other treatments for oligohydramnios in current pregnancy.
Women who smoke.
Fetuses with major congenital anomaly.

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