RecruitingNCT07135284

Real Life Evaluation of the LibAirty Airway Clearance System in Adults With Bronchiectasis (RELACS)

Real Life Evaluation of the LibAirty Airway Clearance System in Adults With Bronchiectasis (RELACS) - A Prospective Study


Sponsor

Synchrony-Medical, Ltd

Enrollment

200 participants

Start Date

Aug 20, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to collect data to assess the use of the LibAirty™ System for improving bronchiectasis symptoms and healthcare resource utilization when it is used at home. The main question this study is trying to answer is: How often do adults with bronchiectasis experience pulmonary exacerbations (flare-ups of their lung condition) while using the LibAirty™ airway clearance system at home? Participants will use the LibAirty™ airway clearance system at home as prescribed by their doctor - the device is not being provided as part of the study. The study will last for 12 months from the time participants begin using LibAirty. During the study period, participants will continue with their usual clinic visits. At some of these regular visits (up to 4 times over the year), participants will be asked to complete short questionnaires about their bronchiectasis symptoms and their experience using LibAirty. At these same visits, the study team will also review participants' medical records and collect information related to their bronchiectasis condition, such as test results, medications, and any hospital or emergency room visits.


Eligibility

Min Age: 21 Years

Inclusion Criteria9

  • Have a radiological diagnosis of Bronchiectasis based on high resolution chest CT scan
  • Have bronchiectasis characterized by either:
  • Daily productive cough (as determined by a treating physician)
  • OR Available documentation from the last 12 months of 2 or more pulmonary exacerbations requiring antibiotic therapy
  • Be at age ≥ 21 years
  • Prescribed and receives the LibAirty system for home use
  • Be on a standard of care treatment plan that includes at least one physician encounter every 6 months
  • No change in treatment for Bronchiectasis in the 2-month period prior to enrollment
  • Signed informed consent

Exclusion Criteria3

  • Inability to independently perform therapy with the LibAirty system as directed
  • Any other condition that, in the opinion of the PI, could jeopardize the safety of the subject or impact the validity of the study results.
  • Pregnancy or planned pregnancy during the expected duration of the trial (12 months).

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Interventions

DEVICEAirway clearance system

The device is prescribed as part of each participant's regular medical care, independently of the study. The study does not assign the device or alter standard treatment. Participants are observed while using the device as part of their usual care.


Locations(3)

University of Alabama at Birmingham

Birmingham, Alabama, United States

Emory University School Of Medicine

Atlanta, Georgia, United States

Medical University of South Carolina

Charleston, South Carolina, United States

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NCT07135284


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