Allogeneic γδT Cells in Glioblastoma

This study is testing a type of immune cell therapy using allogeneic gamma-delta T cells (a specialized type of immune cell from a donor) to treat glioblastoma (a serious brain tumor) that has continued to grow or come back after previous treatment. **You may be eligible if...** - You are between 18 and 70 years old - You have a confirmed diagnosis of glioblastoma (WHO grade IV brain tumor) - Your tumor has continued to grow or has come back after receiving radiation and chemotherapy - Your general health status (Karnofsky scale) is at least 60% - Your organ function, blood counts, and heart function meet required levels - You can have an MRI with contrast **You may NOT be eligible if...** - You have active hepatitis B or C, HIV infection, or other untreated serious infections - You are pregnant or breastfeeding - You have significant organ failure - You have a chronic illness requiring immune-suppressing or hormonal treatment - You have a history of organ transplantation - You have psychiatric conditions that would interfere with participation Talk to your doctor to see if this trial is right for you.