RecruitingNot ApplicableNCT07144761

Evaluating Patient Reported Outcomes and Surgeon Satisfaction With Ziplyft™


Sponsor

Osheru Inc.

Enrollment

200 participants

Start Date

Aug 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of this study is to evaluate patient-reported outcomes, surgeon reported outcomes, bruising, symmetry, the success of tissue adhesive for wound closure, and case time.


Eligibility

Min Age: 35 Years

Inclusion Criteria6

  • Provide signed written consent prior to participation in any study-related procedures.
  • Ability, comprehension, and willingness to follow study instructions, and likely to complete all study visits.
  • Male or female adults, ≥ 35 years old at the Preoperative Visit
  • Willing to return for required follow-up visits.
  • Subjects with excess eyelid skin are eligible to undergo the procedure in the opinion of the investigator.
  • Female subjects must be 1-year postmenopausal, surgically sterilized, or, if of childbearing potential, have a negative urine pregnancy test at the Preoperative Visit. Women of childbearing potential must use an acceptable form of contraception throughout the study. Acceptable methods include at least one of the following: intrauterine (intrauterine device), hormonal (oral, injection, patch, implant, ring), barrier with spermicide (condom, diaphragm), or abstinence.

Exclusion Criteria10

  • Subjects with a current Ptosis diagnosis
  • Subjects with a history of Graves' Disease
  • Subjects with Myasthenia Gravis
  • Subjects that in the opinion of the investigator are anatomically not conducive to using devices (e.g., heavy brow, severe hollowing of the upper eyelid, history of ocular or orbital trauma).
  • Subjects that have had any previous surgery eyelid or eyebrow region.
  • Use of anticoagulation therapy, including, but not limited to Aspirin, NSAIDS, Ibuprofen within 7 days and Xarelto, Warfarin, Enoxaparin, Plavix within 3 days prior to planned study procedure.
  • Active or recent (within 3 months) tobacco user
  • Allergy to adhesive glue
  • Participation in any study of an investigational, interventional product within 30 days prior to the Preoperative Visit or at any time during the study period.
  • Pregnant or nursing females.

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Interventions

DEVICEZiplyft

Ziplyft™ is a Class 1, 510(k) Exempt device for removing excess unwanted eyelid skin using a novel surgical device called Ziplyft™.


Locations(5)

Center for Excellence in Eye Care

Miami, Florida, United States

Vance Thompson Vision

Alexandria, Minnesota, United States

Eye Care Specialists

Kingston, Pennsylvania, United States

Vance Thompson Vision

Sioux Falls, South Dakota, United States

The Eye Centers of Racine and Kenosha, LTD

Kenosha, Wisconsin, United States

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NCT07144761


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