Suprachoroidal Triamcinolone in Macular Edema for Patients With Non-Infectious Uveitis Resistant to Subtenon Triamcinolon
University of Baghdad
20 participants
Sep 1, 2024
INTERVENTIONAL
Conditions
Summary
The goal of this study is to learn if a suprachoroidal triamcinolone injection can treat vision-threatening swelling in the center of the retina (macular edema) caused by non-infectious uveitis, especially in people who did not improve after a standard steroid injection around the eye (sub-Tenon injection). The main questions it aims to answer are: Does vision improve on the eye chart after the injection? Does the injection lower retinal swelling (reduction in thickness) within 3 months? Participants will: Have a pre-treatment check (vision test, slit-lamp exam, and a retinal scan called OCT). Receive one suprachoroidal triamcinolone injection under anesthetics drops in a sterile setting (operating room) with standard monitoring. Return for visits about 1 month and 3 months after treatment for repeat vision tests, and OCT scans. Contact the clinic if they notice pain, redness, new floaters, or worsening vision.
Eligibility
Inclusion Criteria4
- Non-infectious uveitis complicated with macular edema
- Uveitic macular edema of less than four months' duration
- Macular edema persisted despite lack of intra-ocular inflammation
- No response to posterior sub-Tenon triamcinolone acetonide injections
Exclusion Criteria2
- Those with epiretinal membrane-associated macular edema
- Below 18 years
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Interventions
For suprachoroidal injection, we developed a custom-made delivery system to access the potential suprachoroidal space. A 1 mL tuberculin syringe fitted with a 27-gauge needle was prepared, and a plastic sleeve from a 24-26 G IV cannula was placed over the needle as a spacer to control penetration depth.
Locations(1)
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NCT07145008