RecruitingNot ApplicableNCT07145489

Infrared Photobiomodulation in Humans With Epilepsy

An Open Label Pilot Study of Infrared Photobiomodulation in Humans With Epilepsy


Sponsor

Beth Israel Deaconess Medical Center

Enrollment

13 participants

Start Date

Nov 25, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Drug-resistant epilepsy represents roughly 40% of people with epilepsy. It is very challenging to stop seizures in this condition, and the treatment options are limited. This study aims to investigate a new treatment that involves using infra-red light. In animals, this treatment has shown promise as a possible way to reduce seizures, but it has not been tested in humans for this. The investigators are interested to know if it can reduce seizures, and how comfortable it is to be treated with this therapy.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Drug resistant epilepsy
  • Age 18 or older
  • Average seizure rate of at least 2 seizures per month
  • Accurate seizure diary with at least 3 months recorded

Exclusion Criteria5

  • Implanted intracranial neurostimulation device (DBS or RNS)
  • Intracranial shunt
  • Skin photosensitivity
  • Cancer on scalp
  • Taking any medication that can cause photosensitivity

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Interventions

DEVICEphotobiomodulation

a hat with infrared lights will be worn for 30 minutes daily for 6 months


Locations(1)

BIDMC

Boston, Massachusetts, United States

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NCT07145489


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