RecruitingNCT07146698
No Sedation Versus Daily Interruption of Sedation in Chronic Obstructive Pulmonary Disease Mechanically Ventilated Patients- A Prospective Study
Sponsor
Benha University
Enrollment
60 participants
Start Date
Nov 1, 2024
Study Type
OBSERVATIONAL
Conditions
Summary
this study is to compare no-sedation versus daily interruption of sedation (DIS) in Chronic obstructive pulmonary disease (COPD) patients receiving mechanical ventilation upon the ventilator-free days.
Eligibility
Min Age: 18 Years
Inclusion Criteria4
- Patients of both sex aged 18 years or older
- The study will include 60 patients divided into 2 equal groups
- Invasive mechanical ventilation
- Patients with COPD patients (post-bronchodilator FEV1/FVC\< 70, and under follow through the department outpatient clinic) exacerbation admitted to the ICU and required invasive mechanical ventilation were recruited.
Exclusion Criteria4
- Allergy to sedative which will be used
- renal or hepatic impairment
- proven or suspected psychiatric or neurological impairment
- pregnancy
Interventions
BEHAVIORALdaily Interruption of Sedation
The patients will be managed by DIS. Richmond agitation and sedation score (RASS) will be used for monitoring the depth of sedation
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07146698
Related Trials
IMPACT COPD Cohort (China)
NCT073829864 locations
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
NCT07082738363 locations
Long-term Real-world Study of Dupilumab in COPD : Patient Characteristics, Safety and Patient-reported Outcomes
NCT0738071120 locations
Comparing Hydrocortisone and Prednisolone for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD)
NCT0689221014 locations
Study of Patient With Frequent Exacerbations in Moscow
NCT073077811 location