RecruitingNCT07147465

Performance Indicators and Impact on the Care Pathway of Sequencing on the SeqOIA and AURAGEN (Seqogen) Platforms for Oncology Patients

Indicateurs de Performance et Impact Sur le Parcours de Soins du Séquençage Sur Les Plateformes Seqoia et Auragen (Seqogen) Pour Les Patients en Oncologie


Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

3,149 participants

Start Date

Jul 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

As part of the French Genomic Medicine Plan 2025 (FGM), the SeqOIA and AURAGEN platforms were selected to perform high-throughput genomic sequencing. The SONCO (Sequencing Oncology Cohort) project combines their medical and economic evaluations into a single national cohort. Its objective is to assess the impact of genomic sequencing on care pathways and treatment recommendations by collecting indicators related to quality, turnaround time, and patient information. Clinical data are gathered from molecular tumor board reports (via SPICE and HYGEN) and from hospital medical records. This cohort is intended to support public health decision-making and help anticipate the organization of future genomic platforms.


Eligibility

Inclusion Criteria3

  • Patients diagnosed with cancer and referred for high-throughput sequencing
  • Sequencing pre-indication validated: Patients for whom the pre-indication for sequencing the genome, exome, and RNA has been validated by the upstream RCP (Multidisciplinary Tumor Board) since January 1, 2021.
  • Consent for data reuse: Patients who have agreed to the reuse of their medical and genomic data for research purposes and have not opposed this use.

Exclusion Criteria1

  • Opposition to data reuse, unvalidated upstream RCP

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Locations(3)

Centre Leon Berard

Lyon, France

APHP Hôtel Dieu URC Economie de la sante /URC ECO

Paris, France

HOPITAL AP-HP Cochin

Paris, France

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NCT07147465


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