RecruitingNCT07155252

Home-based Oral Glucose Tolerance Test for Type 1 Diabetes Screening

Sponsor

Yale University

Enrollment

60 participants

Start Date

Aug 26, 2025

Study Type

OBSERVATIONAL

Conditions

Type 1 Diabetes

Summary

This study aims at quantifying the accuracy of a self-administered fingerstick based glucose tolerance test (GTT@Home) respect to the gold-standard in-clinic venous plasma measures during the oral glucose tolerance test (OGTT) across a wide range of glycemic values in people at risk for clinical type 1 diabetes (T1D) (carriers of at least one islet autoantibody) or with new onset Stage 3 T1D within 100 days from the diagnosis.

Eligibility

Min Age: 8 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether an at-home version of a blood sugar test (called an oral glucose tolerance test, or OGTT) works just as well as the standard clinic-based test. The goal is to make diabetes screening easier for people at risk of Type 1 diabetes. **You may be eligible if...** - You weigh at least 43 kg (about 95 lbs) - You have at least one islet autoantibody (a marker in the blood that signals risk for Type 1 diabetes) - You were diagnosed with Stage 3 Type 1 diabetes within the last 100 days and are at least 12 years old - You are in generally good health - You can read and understand English **You may NOT be eligible if...** - You are currently pregnant or become pregnant during the study - You take SGLT inhibitor medications (a type of diabetes drug) - You have donated blood in the past 8 weeks Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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