RecruitingNot ApplicableNCT07157397

Effect of a Plant-Focused Diet on Nutritional Status in Malnourished Peritoneal Dialysis Patients

Effect of Plant-Focused Diet on Nutritional Status of Malnourished Patients Undergoing Peritoneal Dialysis in a Selected Hospital Care Setting

Sponsor

National University of Malaysia

Enrollment

100 participants

Start Date

Mar 10, 2026

Study Type

INTERVENTIONAL

Conditions

End Stage Kidney Disease (ESRD)End Stage Renal Disease (ESRD)Peritoneal Dialysis (PD)Malnourished

Summary

The goal of this clinical trial is to determine whether a plant-focused diet improves nutritional and health outcomes of malnourished adults undergoing peritoneal dialysis (PD). It will also learn about the safety of this diet in this population. The main questions it aims to answer are: 1. Does a plant-focused diet improve nutritional status compared to a standard kidney diet in PD patients? 2. What changes occur in anthropometric, biochemical, and dietary measures over 6 months? Researchers will compare the plant-focused diet to a standard-of-care renal diet to see which is more effective in improving nutrition in PD patients. Participants will: * Be randomly assigned to follow the plant-focused diet or the standard diet. * Be monitored for 6 months through in-person visits (aligned with their routine clinic appointments) and virtual check-ins via messages or calls. * Have their progress monitored for changes in outcomes such as nutrition, blood tests, kidney function, and quality of life.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether switching to a plant-focused diet (high in plant protein, low in animal protein) can improve nutrition and reduce inflammation in malnourished patients on peritoneal dialysis — a form of home-based kidney replacement therapy. **You may be eligible if...** - You are an adult (18+) attending a peritoneal dialysis clinic - You have been on peritoneal dialysis for at least 6 months - You have a low protein level in your blood (albumin below 40 g/L) - You have a low BMI (under 25 kg/m²) and signs of malnutrition - You are willing to follow dietary instructions and attend follow-up visits **You may NOT be eligible if...** - You have been hospitalized in the past 3 months - You have an active infection or sepsis - You have had surgery in the past 6 months - You have cancer or a severe inflammatory disease - Your dialysis is not providing adequate clearance (Kt/V below 1.2) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALPlant-Focused Diet Counselling

Individualized dietary counseling conducted with the use of sample meal plans and infographics to guide patients to consume a diet emphasising plant-based protein sources while meeting nutritional requirements for peritoneal dialysis patients.

BEHAVIORALStandard Renal Diet Counselling

Individualized dietary counseling conducted with the use of sample meal plans and infographics based on current guideline recommendations, to guide patients to consume a diet emphasising animal-based protein sources while meeting nutritional requirements for peritoneal dialysis patients.

Locations(1)

Hospital Canselor Tuanku Muhriz UKM

Cheras, Kuala Lumpur, Malaysia

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NCT07157397

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