Risk Assessment for HBV-Related Liver Cancer

This study is looking for people with hepatitis B (a liver infection) who may be at higher risk of developing liver cancer, in order to improve how doctors predict and monitor that risk. **You may be eligible if...** - You test positive for the hepatitis B surface antigen (meaning you carry the hepatitis B virus) - AND at least one of the following applies: your scans show signs of liver scarring (cirrhosis); you have type 2 diabetes; you have a family history of liver cirrhosis or liver cancer; you have drunk heavily for more than 5 years; your liver biopsy shows significant scarring; or your liver stiffness score is high **You may NOT be eligible if...** - You have already been diagnosed with cancer - You have had a liver transplant - You are HIV positive - Your life expectancy is less than 1 year - You have serious organ problems (heart, kidneys, lungs, etc.) or a serious psychiatric condition Talk to your doctor to see if this trial is right for you.