RecruitingNCT07161388

Durvalumab Consolidation After Chemoradiation Therapy for Limited Stage SCLC in China

Durvalumab Consolidation After Chemoradiation Therapy (CRT) for Patients With Limited Stage Small-Cell Lung Cancer in China: A Multicentre, Observational Study (DREAM)


Sponsor

AstraZeneca

Enrollment

200 participants

Start Date

Nov 17, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This prospective, multicentre, observational study aims to assess the effectiveness and safety of durvalumab as consolidation treatment for patients with LS-SCLC who have not progressed following CRT in real-world setting.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether a drug called durvalumab (an immunotherapy) can help prevent small cell lung cancer from coming back after patients in China have completed chemotherapy combined with radiation therapy. Small cell lung cancer (SCLC) is an aggressive type of lung cancer. **You may be eligible if...** - You are 18 or older - You have been diagnosed with limited-stage small cell lung cancer (stages I–III) - Your cancer did not get worse during your chemotherapy and radiation treatment - You completed your chemoradiation within an acceptable timeframe - You are in reasonably good physical health **You may NOT be eligible if...** - Your cancer progressed during or after chemoradiation - You have received prior immunotherapy - You have severe autoimmune disease or conditions that require immune-suppressing medications - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(24)

Research Site

Beijing, China

Research Site

Cangzhou, China

Research Site

Dongguan, China

Research Site

Fuzhou, China

Research Site

Guangzhou, China

Research Site

Guangzhou, China

Research Site

Huzhou, China

Research Site

Jinan, China

Research Site

Jinan, China

Research Site

Nanjing, China

Research Site

Nanning, China

Research Site

Ningbo, China

Research Site

Shanghai, China

Research Site

Shanghai, China

Research Site

Shenyang, China

Research Site

Shenzhen, China

Research Site

Shijiazhuang, China

Research Site

Taiyuan, China

Research Site

Tianjing, China

Research Site

Wuhan, China

Research Site

Wuxi, China

Research Site

Yangzhou, China

Research Site

Zhengzhou, China

Research Site

Zhengzhou, China

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NCT07161388


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