RecruitingPhase 2NCT07162181

Long-Term Safety of Pirtobrutinib in Participants With Previously Treated Types of Blood Cancers

Long-Term Safety of Pirtobrutinib in Participants From Study J2N-MC-JZNJ With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma


Sponsor

Eli Lilly and Company

Enrollment

13 participants

Start Date

Aug 7, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to find out more about the long-term safety of pirtobrutinib in participants with previously treated types of blood cancer. Participants must have chronic lymphocytic leukemia, small lymphocytic lymphoma, or non-Hodgkins lymphoma. The study is open to those who completed the original study - J2N-MC-JZNJ (NCT04849416) and continue to benefit from treatment. Treatment will be given every 12 weeks and this study is expected to last about 5 years.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study collects long-term safety data on a drug called pirtobrutinib in people with blood cancers (such as certain types of leukemia or lymphoma) who are already taking it in a separate, related clinical trial. It is an extension study designed to keep track of how safe the drug is over a longer period. **You may be eligible if...** - You are already enrolled and actively receiving pirtobrutinib in the originator study (JZNJ) - You agree to follow contraception requirements during the study **You may NOT be eligible if...** - You are pregnant, planning to become pregnant, or breastfeeding during the study or shortly after stopping treatment Note: This is a continuation study. You must already be enrolled in the related trial to participate. Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGPirtobrutinib

Administered orally.


Locations(6)

Beijing Cancer hospital

Beijing, China

Sun Yat-sen University Cancer Center

Guangzhou, China

Harbin Medical University Cancer Hospital

Harbin, China

Shanghai East Hospital

Shanghai, China

Blood Institute of the Chinese Academy of Medical science

Tianjin, China

Union Hospital Tongji Medical College Huazhong University of Science and Technology

Wuhan, China

View Full Details on ClinicalTrials.gov

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NCT07162181


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