RecruitingNot ApplicableNCT07162935

Cigar Legislation and Regulation in Tobacco for the Young (Project CLARITY)

Addiction Potential, Flavoring Content, and Substitutability of Concept Flavored Cigarillos


Sponsor

University of Oklahoma

Enrollment

300 participants

Start Date

Mar 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This clinical trial will recruit young adults who currently use cigarillos and examine the smoking behavior and perceptions of different flavored cigarillos, product ingredients/additives impacting these perceptions, and simulated tobacco use outcomes (quitting, switching) in various policy scenarios where different types of flavors are available on the market.


Eligibility

Min Age: 18 YearsMax Age: 24 Years

Inclusion Criteria6

  • Ages 18 to 24
  • Report past 30-day use of a cigarillo
  • Ability to read English at least an 8th grade level
  • No immediate plans to quit using tobacco
  • At least 1 prior experience with a flavored tobacco product
  • U.S. Citizen or permanent resident of the United States.

Exclusion Criteria5

  • Current use of smoking cessation pharmacotherapy or nicotine replacement therapy;
  • Pregnant, planning to become pregnant, or currently breastfeeding;
  • Past or current clinically significant heart disease or hypertension, or other smoking-related disease that could preclude successful study completion;
  • Inability to abstain from nicotine/tobacco products for at least 12 hours
  • Unwillingness to use the research cigarillos in the lab

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Interventions

OTHERCigarillo brand 1

Participants will be assessed on puffing behavior, subjective effects, and exhaled carbon monoxide when assigned to using one of three cigarillo brands. Additives and ingredients of the cigarillo used will also be assessed

OTHERCigarillo brand 2

Participants will be assessed on puffing behavior, subjective effects, and exhaled carbon monoxide when assigned to using one of three cigarillo brands. Additives and ingredients of the cigarillo used will also be assessed

OTHERCigarillo brand 3

Participants will be assessed on puffing behavior, subjective effects, and exhaled carbon monoxide when assigned to using one of three cigarillo brands. Additives and ingredients of the cigarillo used will also be assessed


Locations(2)

University of Oklahoma Health Campus

Oklahoma City, Oklahoma, United States

West Virginia University

Morgantown, West Virginia, United States

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NCT07162935


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