RecruitingPhase 2NCT07167160

Chemo-immunotherapy for Cervical Cancer Stage IIICp Trial

Camrelizumab Combined With Chemotherapy for Adjuvant Treatment of Cervical Cancer Patients With Pathologically Confirmed Lymph Node Positivity After Stage Surgery: A Prospective, Single-Arm, Multicenter, Phase II Clinical Trial


Sponsor

Women's Hospital School Of Medicine Zhejiang University

Enrollment

59 participants

Start Date

Mar 10, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Efficacy evaluation of camrelizumab combined with chemotherapy for adjuvant treatment of patients with pathologically confirmed lymph node-positive cervical cancer after staging surgery.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 70 Years

Inclusion Criteria3

  • Patients with cervical cancer staged FIGO2018 IIIC1p or IIIC2p after radical surgery;
  • Positive PD-L1 expression;
  • ECOG score ≤1

Exclusion Criteria5

  • Positive parametrium or surgical margin;
  • Incomplete radical surgery;
  • Residual target lesions;
  • Active autoimmune disease or autoimmune disease requiring systemic treatment;
  • Previous treatment with immune checkpoint inhibitors.

Interventions

DRUGCamrelizumab combined with chemotherapy

Camrelizumab combined with chemotherapy for adjuvant treatment of patients with pathologically confirmed lymph node-positive cervical cancer after staging surgery


Locations(1)

Women's Hospital, School of Medicine, Zhejiang University

Hangzhou, Zhejiang, China

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NCT07167160


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