RecruitingPhase 2NCT07167160

Chemo-immunotherapy for Cervical Cancer Stage IIICp Trial

Camrelizumab Combined With Chemotherapy for Adjuvant Treatment of Cervical Cancer Patients With Pathologically Confirmed Lymph Node Positivity After Stage Surgery: A Prospective, Single-Arm, Multicenter, Phase II Clinical Trial


Sponsor

Women's Hospital School Of Medicine Zhejiang University

Enrollment

59 participants

Start Date

Mar 10, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Efficacy evaluation of camrelizumab combined with chemotherapy for adjuvant treatment of patients with pathologically confirmed lymph node-positive cervical cancer after staging surgery.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying whether adding immunotherapy (a drug that activates the immune system to fight cancer) to the standard treatment of chemotherapy and radiation helps prevent cervical cancer from coming back after surgery. It specifically focuses on patients whose cancer spread to nearby lymph nodes. **You may be eligible if...** - You have cervical cancer that was staged as FIGO 2018 stage IIIC1p or IIIC2p (meaning lymph node spread was found on pathology after surgery) - You had complete radical surgery (total removal of the uterus and affected tissue) - Your cancer tests positive for PD-L1 (a protein that suggests immunotherapy may work) - You are in good overall health (ECOG score 0 or 1) **You may NOT be eligible if...** - Cancer was found at the surgical edges (positive margins) or in the tissue surrounding the cervix - Your surgery was incomplete - There is remaining visible cancer after surgery - You have active autoimmune disease - You have previously received immunotherapy Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGCamrelizumab combined with chemotherapy

Camrelizumab combined with chemotherapy for adjuvant treatment of patients with pathologically confirmed lymph node-positive cervical cancer after staging surgery


Locations(1)

Women's Hospital, School of Medicine, Zhejiang University

Hangzhou, Zhejiang, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07167160


Related Trials