RecruitingNCT07167225

Carcinogen and Toxicant Exposure Among Young Adults Who Co-Use E-cigarettes and Cannabis (Co-Tox Study)


Sponsor

Roswell Park Cancer Institute

Enrollment

150 participants

Start Date

Apr 3, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This study evaluates the amount of nicotine, cannabis, and toxicants linked to the use of nicotine e-cigarette and/or cannabis products in the blood and urine of young adult users as well as the cannabis and nicotine use behaviors of consumers.


Eligibility

Min Age: 18 YearsMax Age: 25 Years

Inclusion Criteria8

  • Young adult (18-25 years old).
  • Ability to read and write in English.
  • Participants must fall into one of the following groups (based on self-report):
  • Predominant e-cigarette consumer: defined as using nicotine-containing e-cigarettes daily for the past six months but not having used other nicotine containing products more than weekly or cannabis products for the past month.
  • Predominant cannabis consumer: defined as using cannabis at least 3x/week for the past six months in any form, including smoking, vaping, and oral use, with no more than weekly use of any nicotine or tobacco products.
  • E-cigarette-cannabis co-consumers: defined as daily use of nicotine e-cigarettes and use of cannabis at least 3x/week, including smoking, vaping, and oral use, for at least the past six months, with no use of other nicotine containing products more than weekly.
  • No self-reported diagnosis of kidney disease (current, or within the past year prior to the study visit).
  • Participants must understand the voluntary nature of this study and sign a written informed consent form before proceeding with study activities.

Exclusion Criteria3

  • Individuals under the age of 18 or over the age of 25.
  • Currently pregnant or breastfeeding (female participants).
  • Unwilling or unable to follow protocol requirements

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Interventions

OTHEREffectiveness of different recruitment approaches

Subjects will asked which type of recruitment material they've seen when completing the screening survey

OTHERChoice of study completion locations

subjects will choose location when coordinator calls to schedule appointment

OTHERCannabis Engagement Assessment

Self reported measure of current cannabis use that contains 30 questions assessing quantity, frequency of use and method of consumption in the past 30 days.

OTHERE-cigarette dependence Scale

A 22-item questionnaire measuring e-cigarette dependence. Higher scores indicate greater dependence.


Locations(1)

Roswell Park Comprehensive Cancer Center

Buffalo, New York, United States

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NCT07167225


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