RecruitingPhase 2NCT07171606

A Phase II Study of SSGJ-706 Monotherapy and Combination Therapy in Advanced Non-Small Cell Lung Cancer(NSCLC) Patients


Sponsor

Shenyang Sunshine Pharmaceutical Co., LTD.

Enrollment

240 participants

Start Date

Oct 24, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study includes two parts, part 1 is SSGJ-706 monotherapy therapy for advanced NSCLC and part 2 is SSGJ-706 combination therapy for advanced NSCLC


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This phase II trial is testing a drug called SSGJ-706, alone or in combination with other treatments, in people with advanced non-small cell lung cancer (NSCLC). It is looking for the best dose and checking how well the drug works. **You may be eligible if...** - You are 18 or older with advanced or metastatic NSCLC confirmed by biopsy or lab test - You are in good physical condition (ECOG 0–1) - You are expected to live at least 3 months **You may NOT be eligible if...** - You have active or symptomatic brain metastases - You still have significant side effects from prior cancer treatment (other than hair loss or mild fatigue) - Your organ function (blood, kidney, liver) is inadequate - You are pregnant or breastfeeding - You are allergic to SSGJ-706 Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSSGJ-706

PD-1/PD-L1 bispecific antibody

DRUGpemetrexed /carboplatin

chemotherapy

DRUGCarboplatin/Paclitaxel

chemotherapy

DRUGPD-1 Inhibitor + Chemotherapy

control group


Locations(1)

Institute of The Shanghai Pulmonary Hospital

Shanghai, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT07171606


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