RecruitingPhase 2NCT07171606
A Phase II Study of SSGJ-706 Monotherapy and Combination Therapy in Advanced Non-Small Cell Lung Cancer(NSCLC) Patients
Sponsor
Shenyang Sunshine Pharmaceutical Co., LTD.
Enrollment
240 participants
Start Date
Oct 24, 2025
Study Type
INTERVENTIONAL
Conditions
Summary
This study includes two parts, part 1 is SSGJ-706 monotherapy therapy for advanced NSCLC and part 2 is SSGJ-706 combination therapy for advanced NSCLC
Eligibility
Min Age: 18 YearsMax Age: 75 Years
Plain Language Summary
Simplified for easier understanding
This phase II trial is testing a drug called SSGJ-706, alone or in combination with other treatments, in people with advanced non-small cell lung cancer (NSCLC). It is looking for the best dose and checking how well the drug works.
**You may be eligible if...**
- You are 18 or older with advanced or metastatic NSCLC confirmed by biopsy or lab test
- You are in good physical condition (ECOG 0–1)
- You are expected to live at least 3 months
**You may NOT be eligible if...**
- You have active or symptomatic brain metastases
- You still have significant side effects from prior cancer treatment (other than hair loss or mild fatigue)
- Your organ function (blood, kidney, liver) is inadequate
- You are pregnant or breastfeeding
- You are allergic to SSGJ-706
Talk to your doctor to see if this trial is right for you.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
DRUGSSGJ-706
PD-1/PD-L1 bispecific antibody
DRUGpemetrexed /carboplatin
chemotherapy
DRUGCarboplatin/Paclitaxel
chemotherapy
DRUGPD-1 Inhibitor + Chemotherapy
control group
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07171606