RecruitingNCT07175285

A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants

Prospective, Observational Study in Participants With Active Systemic Lupus Erythematosus (SLE) (Including Lupus Nephritis) With Inadequate Response to Glucocorticoids and At Least 2 Immunosuppressants

Sponsor

Bristol-Myers Squibb

Enrollment

223 participants

Start Date

Oct 8, 2025

Study Type

OBSERVATIONAL

Conditions

Systemic Lupus Erythematosus (SLE)

Summary

The purpose of this study is to characterize the efficacy and safety of current standard of care treatment options in participants with active systemic lupus erythematosus (SLE; including lupus nephritis) with inadequate response to glucocorticoids and at least two immunosuppressants

Eligibility

Min Age: 16 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Current standard of care treatment options for people with systemic lupus erythematosus (sle). The study is currently recruiting participants at 62 locations. People eligible for this study include aged 16 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGCurrent standard of care treatment options

According to the product label

Locations(65)

Arizona Arthritis & Rheumatology Associates (AARA), P.C. - Mesa

Mesa, Arizona, United States

Local Institution - 0054

La Jolla, California, United States

Local Institution - 0001

La Palma, California, United States

Local Institution - 0071

Los Angeles, California, United States

Rheumatology Center of San Diego

San Diego, California, United States

Centre for Rheumatology, Immunology and Arthritis

Fort Lauderdale, Florida, United States

South Florida Rheumatology

Hollywood, Florida, United States

LIFE Clinical Trials

Margate, Florida, United States

One- Rheumatology

Palm Beach Gardens, Florida, United States

Local Institution - 0069

Atlanta, Georgia, United States

Willow Rheumatology & Wellness

Willowbrook, Illinois, United States

Arthritis & Rheumatism Associates

Rockville, Maryland, United States

Local Institution - 0034

Ann Arbor, Michigan, United States

AA MRC

Grand Blanc, Michigan, United States

Local Institution - 0070

Kalispell, Montana, United States

Sahni Rheumatology & Therapy

West Long Branch, New Jersey, United States

Kings County Hospital Center - Brooklyn

Brooklyn, New York, United States

DJL Clinical Research, PLLC

Charlotte, North Carolina, United States

Local Institution - 0037

Durham, North Carolina, United States

Oklahoma Medical Research Foundation

Oklahoma City, Oklahoma, United States

Local Institution - 0052

Philadelphia, Pennsylvania, United States

Murfreesboro Medical Clinic

Murfreesboro, Tennessee, United States

Arthritis Care of Texas - Corpus Christi

Corpus Christi, Texas, United States

El Paso Medical Research Institute (MedResearch, Inc)

El Paso, Texas, United States

Local Institution - 0051

Van Vleck, Texas, United States

Instituto Médico CER

Quilmes, Buenos Aires, Argentina

Centro de Investigaciones Medicas Tucuman

San Miguel de Tucumán, Tucumán Province, Argentina

Organización Médica de Investigación (OMI)

Buenos Aires, Argentina

Instituto De Reumatologia - IR Medical Center - Hospital de Dia

Mendoza, Argentina

Local Institution - 0005

Porto Alegre, Rio Grande do Sul, Brazil

Local Institution - 0007

Porto Alegre, Rio Grande do Sul, Brazil

Local Institution - 0042

São Paulo, Brazil

Centre hospitalier de l'Université Laval

Calgary, Alberta, Canada

St. Joseph's Hospital

London, Ontario, Canada

The Ottawa Hospital - General Campus

Ottawa, Ontario, Canada

Local Institution - 0038

Sherbrooke, Quebec, Canada

CHU Hopitaux de Bordeaux - Groupe Hospitalier Pellegrin

Bordeaux, France

Hôpitaux Universitaires de Strasbourg - Hôpital de Hautepierre

Strasbourg, France

Hôpital Saint-Antoine

Paris, Île-de-France Region, France

Local Institution - 0041

Kiel, Schleswig-Holstein, Germany

Local Institution - 0043

Mainz, Germany

Meir Medical Center

Kfar Saba, M, Israel

Sheba Medical Center

Ramat Gan, TA, Israel

Rambam Medical Center

Haifa, Israel

Carmel Medical Center

Haifa, Israel

Rabin Medical Center - Hasharon Hospital

Petah Tikva, Israel

Local Institution - 0025

Tel Aviv, Israel

Azienda Ospedaliero-Universitaria di Ferrara - Arcispedale Sant'Anna

Ferrara, RE, Italy

Azienda Ospedaliera Ordine Mauriziano di Torino

Torino, TO, Italy

ASST degli Spedali Civili di Brescia

Brescia, Italy

Local Institution - 0053

Sendai, Miyagi, Japan

Toyama University

Toyama, Toyama, Japan

Hospital of the University of Occupational and Environmental Health, Japan

Kitakyushu-Shi, Japan

Local Institution - 0055

Wakayama, Japan

Local Institution - 0046

San Juan, PR, Puerto Rico

Hospital de Merida

Mérida, Badajoz, Spain

Hospital Clínic de Barcelona

Barcelona, Spain

Local Institution - 0072

Lund, Skåne County, Sweden

Local Institution - 0073

Solna, Stockholm County, Sweden

Local Institution - 0074

Örebro, Sweden

Oxford University Hospitals NHS Trust - Churchill Hospital

Oxford, OXF, United Kingdom

Royal National Hospital for Rheumatic Diseases-Bath

Bath, SOM, United Kingdom

The Royal Wolverhampton NHS Trust - New Cross Hospital

Wolverhampton, West Midlands, United Kingdom

The Royal Free London NHS Foundation Trust - The Royal Free Hospital

London, United Kingdom

King's College Hospital NHS Foundation Trust

London, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT07175285

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