RecruitingNot ApplicableNCT07177495

Radiographic and Histomorphometric Assessment for Maxillary Sinus Floor Elevation and Augmentation Using A Mixture of 1:1 Autogenous Bone With Deproteinized Bovine Bone Particulate Versus Deproteinized Bovine Bone Particulate

Radiographic and Histomorphometric Assessment for Maxillary Sinus Floor Elevation and Augmentation Using A Mixture of 1:1 Autogenous Bone With Deproteinized Bovine Bone Particulate Versus Deproteinized Bovine Bone Particulate: A Randomized Clinical Trial


Sponsor

Cairo University

Enrollment

26 participants

Start Date

Apr 10, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

two group of patients with atrophied posterior maxilla that need implant/s placement. one group will be subjected to maxillary sinus floor elevation using 1:1 mixture of autogenous bone and deproteinized bovine bone particulate while the other will be subjected to maxillary sinus floor elevation using deproteinized bovine bone particulate alone.


Eligibility

Min Age: 30 Years

Inclusion Criteria4

  • Patients of both genders requiring implants placement in atrophied posterior maxilla with residual bone height less than 5mm .
  • Patients of age older than 30 years old.
  • Patients with adequate Inter-arch space.
  • Patients who were willing and fully capable to comply with the study protocol.

Exclusion Criteria6

  • Patients suffering from any sinus pathosis
  • Heavy smokers (> than 10 cigarettes a day)
  • Patients with parafunctional habits
  • Patients with uncontrolled systemic diseases.
  • Patients with poor oral hygiene
  • Patients with mental instabilities or psychic patients

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Interventions

PROCEDUREmaxillary sinus floor elevation using Open Maxillary sinus floor elevation and Augmentation using Deproteinized Bovine Bone Particulate

Phase 1: Grafting * after administration of Local anesthesia (articaine hydrochloride 68 mg/1.7 ml \+ adrenaline0.017 mg), full-thickness mucoperiosteal flap originating from the mid-crestal area or slightly toward the palate side would be opened. * lateral window will be created in the maxillary bone to allow for adequate access to the sinus membrane. * The membrane will be carefully elevated using a sinus elevator. * bone graft will be placed into the sinus cavity using Autogenous Bone with Deproteinized Bovine Bone Particulate. * collagen membrane will be secured in place using resorbable sutures or tacks if necessary. Phase 2 (delayed implant placement and core biopsy harvesting 6 Months Postoperative): * full thickness mucoperiosteal flap originating from the mid-crestal area or slightly towards palate side would be opened. * core biopsy would be harvested using trephine burs from the site of implant placement prior to drilling, to be sent to the Lab for Histological assessment.

PROCEDUREOpen Maxillary sinus floor elevation and Augmentation using A Mixture of 1:1 Autogenous Bone with Deproteinized Bovine Bone Particulate

Phase 1: Grafting * After maxillary sinus floor elevation, Mixture of 1:1 Autogenous Bone with Deproteinized Bovine Bone Particulate will be placed in the sinus cavity and secured in place using resorbable sutures or tacks if necessary. * Phase 2 (delayed implant placement and core biopsy harvesting 6 Months Postoperative): * full thickness mucoperiosteal flap originating from the mid-crestal area or slightly towards palate side would be opened. • core biopsy would be harvested using trephine burs from the site of implant placement prior to drilling, to be sent to the Lab for Histological assessment.


Locations(1)

faculty of oral and dental medicine, Cairo university

Cairo, Giza Governorate, Egypt

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NCT07177495