Radiographic and Histomorphometric Assessment for Maxillary Sinus Floor Elevation and Augmentation Using A Mixture of 1:1 Autogenous Bone With Deproteinized Bovine Bone Particulate Versus Deproteinized Bovine Bone Particulate
Radiographic and Histomorphometric Assessment for Maxillary Sinus Floor Elevation and Augmentation Using A Mixture of 1:1 Autogenous Bone With Deproteinized Bovine Bone Particulate Versus Deproteinized Bovine Bone Particulate: A Randomized Clinical Trial
Cairo University
26 participants
Apr 10, 2025
INTERVENTIONAL
Conditions
Summary
two group of patients with atrophied posterior maxilla that need implant/s placement. one group will be subjected to maxillary sinus floor elevation using 1:1 mixture of autogenous bone and deproteinized bovine bone particulate while the other will be subjected to maxillary sinus floor elevation using deproteinized bovine bone particulate alone.
Eligibility
Inclusion Criteria4
- Patients of both genders requiring implants placement in atrophied posterior maxilla with residual bone height less than 5mm .
- Patients of age older than 30 years old.
- Patients with adequate Inter-arch space.
- Patients who were willing and fully capable to comply with the study protocol.
Exclusion Criteria6
- Patients suffering from any sinus pathosis
- Heavy smokers (> than 10 cigarettes a day)
- Patients with parafunctional habits
- Patients with uncontrolled systemic diseases.
- Patients with poor oral hygiene
- Patients with mental instabilities or psychic patients
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Interventions
Phase 1: Grafting * after administration of Local anesthesia (articaine hydrochloride 68 mg/1.7 ml \+ adrenaline0.017 mg), full-thickness mucoperiosteal flap originating from the mid-crestal area or slightly toward the palate side would be opened. * lateral window will be created in the maxillary bone to allow for adequate access to the sinus membrane. * The membrane will be carefully elevated using a sinus elevator. * bone graft will be placed into the sinus cavity using Autogenous Bone with Deproteinized Bovine Bone Particulate. * collagen membrane will be secured in place using resorbable sutures or tacks if necessary. Phase 2 (delayed implant placement and core biopsy harvesting 6 Months Postoperative): * full thickness mucoperiosteal flap originating from the mid-crestal area or slightly towards palate side would be opened. * core biopsy would be harvested using trephine burs from the site of implant placement prior to drilling, to be sent to the Lab for Histological assessment.
Phase 1: Grafting * After maxillary sinus floor elevation, Mixture of 1:1 Autogenous Bone with Deproteinized Bovine Bone Particulate will be placed in the sinus cavity and secured in place using resorbable sutures or tacks if necessary. * Phase 2 (delayed implant placement and core biopsy harvesting 6 Months Postoperative): * full thickness mucoperiosteal flap originating from the mid-crestal area or slightly towards palate side would be opened. • core biopsy would be harvested using trephine burs from the site of implant placement prior to drilling, to be sent to the Lab for Histological assessment.
Locations(1)
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NCT07177495