Time to Ambulation After ProGlide Closure
Optimizing Time to Ambulation After ProGlide Closure of Femoral Access: A Randomized Controlled Trial
Chinese Academy of Medical Sciences, Fuwai Hospital
300 participants
Oct 1, 2025
INTERVENTIONAL
Conditions
Summary
Transradial access has become the standard for coronary procedures due to fewer vascular complications and shorter bed rest, yet transfemoral access remains essential for complex peripheral interventions requiring larger sheaths and stronger support. Vascular closure devices (VCDs), particularly suture-mediated devices such as ProGlide, have improved femoral access by reducing hemostasis time, ambulation delay, and patient discomfort. Although early ambulation after ProGlide closure has been reported, current practice varies widely, and the relationship between ambulation timing and vascular complications remains unclear. This trial aims to evaluate the effect of different ambulation times after ProGlide closure in transfemoral peripheral angiography or intervention, with the goal of identifying the optimal time to ambulation that balances safety and efficiency.
Eligibility
Plain Language Summary
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Interventions
Ambulation time after femoral artery access site closure using the ProGlide vascular closure device was assigned to 2 hours, 6 hours, or 12 hours post-procedure.
Locations(1)
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NCT07179536