RecruitingNot ApplicableNCT07180849

Comparing the Antiplaque Effects of Novel Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients.

Comparing the Antiplaque Efficacy of Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients-A Triple Blind Randomised Controlled Trial.

Sponsor

Pakistan Institute of Medical Sciences

Enrollment

20 participants

Start Date

Nov 1, 2025

Study Type

INTERVENTIONAL

Conditions

Dental Plaque Accumulation Nanoparticles Fluoride Varnishes

Summary

In this study the investigators aimed to explore the antibiofilm effect of fluoride varnish loaded with titania nanoparticles synthesized from moringa oleifera leaves extract vs conventional fluoride varnish in multibracket fixed orthodontic patients.

Eligibility

Min Age: 16 YearsMax Age: 30 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Fluoride varnish and a procedure called Novel titania nanoparticle infused fluoride varnish for people with dental plaque accumulation, fluoride varnishes, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 16 Years to 30 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREFluoride varnish

Group A will receive conventional fluoride varnish for antiplaque effects.Plaque will be assessed quantitatively by modified plaque index.

PROCEDURENovel titania nanoparticle infused fluoride varnish

Group B will receive topical application of titania nanoparticle infused fluoride varnish for antiplaque effects.Plaque will be assessed quantitatively by modified plaque index.