Comparing the Antiplaque Effects of Novel Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients.
Comparing the Antiplaque Efficacy of Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients-A Triple Blind Randomised Controlled Trial.
Pakistan Institute of Medical Sciences
20 participants
Nov 1, 2025
INTERVENTIONAL
Conditions
Summary
In this study the investigators aimed to explore the antibiofilm effect of fluoride varnish loaded with titania nanoparticles synthesized from moringa oleifera leaves extract vs conventional fluoride varnish in multibracket fixed orthodontic patients.
Eligibility
Inclusion Criteria4
- Patients planned for fixed orthodontic treatment.
- Patients within age group 16-30 years.
- Patient with no history of previous orthodontic treatment.
- Patients with no active periodontal diseases.
Exclusion Criteria3
- Patient undergoing any antibiotic therapy.
- Patients with any craniofacial abnormality.
- Patient with mixed dentition
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Interventions
Group A will receive conventional fluoride varnish for antiplaque effects.Plaque will be assessed quantitatively by modified plaque index.
Group B will receive topical application of titania nanoparticle infused fluoride varnish for antiplaque effects.Plaque will be assessed quantitatively by modified plaque index.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07180849