RecruitingNot ApplicableNCT07182240

Pilot Study of Line-Field Confocal Optical Coherence Tomography for Detection of Mohs Micrographic Surgery Margins of Basal Cell Carcinomas


Sponsor

Roswell Park Cancer Institute

Enrollment

60 participants

Start Date

Dec 22, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

To assess the feasibility and provide information on the utility of noninvasive line field confocal optical coherence tomography (LC-OCT) for the presurgical assessment of Mohs micrographic surgery sites in patients undergoing removal of cutaneous basal cell carcinomas (BCC).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a new skin imaging technology called line-field confocal optical coherence tomography (LC-OCT) to see if it can accurately identify basal cell carcinoma (a common type of skin cancer) before and during Mohs surgery, potentially reducing the need for multiple surgical stages. **You may be eligible if...** - You are 18 or older - You have been diagnosed with a superficial basal cell carcinoma (a specific, less invasive type of skin cancer) - You are scheduled for Mohs surgery as recommended by your dermatologist **You may NOT be eligible if...** - You have a known allergy to mineral oil (used during imaging) - You have uncontrolled serious health conditions such as active infections, heart failure, or unstable angina - Your skin cancer is not the superficial subtype or is not appropriate for Mohs surgery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICELC-OCT Imaging

handheld imaging device will take high resolution images of lesion


Locations(1)

Roswell Park Comprehensive Cancer Center

Buffalo, New York, United States

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NCT07182240


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