Activities-based Locomotor Training in Children With Cerebral Palsy
Efficacy of Activities-based Locomotor Training in Children With Cerebral Palsy.
Baylor University
19 participants
Jan 11, 2026
INTERVENTIONAL
Conditions
Summary
This project aims to improve the quality of life and functional outcomes for young non-ambulatory children with Cerebral Palsy (CP) by investigating the efficacy of an Activities-Based Locomotor Training (AB-LT) program compared to usual care. By targeting the body structures, activities, and participation components of the World Health Organization's International Classification of Functioning, Disability, and Health (ICF) framework, this study seeks to enhance our understanding of neuroplasticity and motor learning in this population, offering a novel approach to rehabilitation. Results from this research will lead to more effective, individualized therapies that improve motor function, reduce disability, and ultimately lower the long-term healthcare needs associated with CP.
Eligibility
Inclusion Criteria4
- Able to hold their head upright for 5 seconds when supported at the trunk in sitting (the minimal amount of head control necessary for safe walking on the partial body weight support system during the AB-LT intervention);
- Non-ambulatory or not walking as primary means of mobility;
- Willing to attend the AB-LT intervention at Fortis Therapy Center in Dripping Springs, Texas for 3 hours/ day, 5 days/week, for 3 weeks; and
- Willing to commit to a total of 7 weeks of the study, and to continue their usual care during the time period in which they are not enrolled in the AB-LT intervention.
Exclusion Criteria3
- Surgery or botulinum toxin injections in the previous 6 months;
- Uncontrolled epilepsy; and
- Uncontrolled cardiovascular disease
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Interventions
Activities-based locomotor training involves placing the child in a partial body-weight supported (PBWS) system over a treadmill. The child is given assistance by trained clinicians to attempt standing and walking on the treadmill for 1 hour. The child then participates in play-based activities aimed to foster independence in an overground (regular) environment for 1 hour. The final hour of the 3-hour session is conducted in the PBWS system with a focus on standing and walking.
In this intervention, the child will attend their usual physical therapy sessions.
Locations(1)
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NCT07184411