RecruitingNot ApplicableNCT07186023

Effects of Mindfulness or Brain Stimulation Intervention for Late-life Adults in Taiwan Urban and Rural Areas

Intervention Evaluation for Late-life Depression in Taiwan Urban and Rural Areas: Long-term Tracking and Prediction of Non-pharmaceutical Interventions by Smart AI Technologies


Sponsor

National Health Research Institutes, Taiwan

Enrollment

124 participants

Start Date

Aug 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This randomized controlled trial will examine the effects of mindfulness-based interventions and brain stimulation interventions on cognitive function and psychological well-being in older adults. The study will employ a comprehensive assessment approach incorporating psychological evaluations, behavioral assessments, psychophysiological measurements, and neuroimaging analyses to characterize the outcome of nonpharmaceutical interventions in improving geriatric well-being or reducing depression severity.


Eligibility

Min Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This study in Taiwan is testing two brain health interventions for older adults — mindfulness meditation and non-invasive brain stimulation — to see which better improves thinking and reduces depression risk, especially in urban versus rural communities. **You may be eligible if...** - You have at least a basic level of education and can communicate normally - You have normal or corrected vision and hearing - You are right-handed - For the brain stimulation group: you have a diagnosis of major depressive disorder from a psychiatrist **You may NOT be eligible if...** - You have dementia, epilepsy, stroke, brain injury, or Parkinson's disease - You have metal implants (like a pacemaker or cochlear implant) that make MRI unsafe - You have claustrophobia, alcohol or drug dependence, or major physical illness - You are pregnant or might be pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALMBSR

Mindfulness-Based Stress Reduction

BEHAVIORALMBWC

Mindfulness-Based Well-Being Curriculum

BEHAVIORALMBCI

Mindfulness-Based Curriculum for Insomnia

DEVICEBSI

Brain Stimulation Intervention


Locations(2)

Shuang Ho Biomedical Park, Taipei Medical University

New Taipei City, Taiwan

National Center for Geriatrics and Welfare Research

Yunlin, Taiwan

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NCT07186023